STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3556Putative outer membrane TonB-dependent receptor,probably involved in iron metabolism. 20% Similar to the IrgA enterobactine outer membrane receptor in V. cholerae. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC VIBRIOBACTIN AN IRON CHELATIN SIDEROPHORE THAT ALLOWS V.CHOLERAE TO EXTRACT IRON FROM THE ENVIRONMENT. SWISSPROT:IRGA_VIBCH:P27772. 21% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1; Specificity unclear. (646 aa)    
Predicted Functional Partners:
azo3555
TonB-dependent receptor, putative; COBALAMIN RECEPTOR PROTEIN; Specificity unclear.
 
    
0.661
azo0235
Conserved hypothetical membrane protein. Homology to an orf of Rubrivivax gelatinosus of 55% (gi|47575633|ref|ZP_00245668.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. 1 TMHs; Conserved hypothetical protein.
   
 
 0.644
tolA
Conserved hypothetical membrane protein. Homology to tolA of N. europaea of 39% (trembl|Q82XP0). no domains predicted InterPro: Proline-rich region (IPR000694) no signal peptide 1 TMHs; Conserved hypothetical protein.
   
 
 0.644
tonB1
Putative TonB protein. Homology to tonb2 of P. aeruginosa of 39% (TREMBL:Q9RMT3). To complete transport of bound iron across the inner membrane, a second receptor complex is needed. The major component of this is tonB, a 27kDa protein that facilitates energy transfer from the proton motive force to outer receptors Pfam: Gram-negative bacterial TonB protein no signal peptide 1 TMH; Function unclear.
   
 
 0.644
azo0708
Conserved hypothetical secreted protein. Homology to ne1626 of N. europaea of 46% (trembl|Q82U75) no domains predicted signal peptide TMH in signal peptide; Conserved hypothetical protein.
   
 
 0.644
tonB2
Periplasmic biopolymer transport protein linking inner and outer membranes; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
   
 
 0.644
tolB
Putative translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
    
 
 0.621
azo3554
Putative ABC transporter system, permease protein; Region start changed from 3899167 to 3899122 (-45 bases); Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
     0.568
azo3746
Hypothetical secreted protein. No homology to the data bank. No domains predicted. signal peptide no TMHs.
   
 
 0.545
parA1
ParA family protein; Putative chromosome partitioning protein; High confidence in function and specificity.
    
   0.526
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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