STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
emrEHypothetical multidrug efflux transporter protein; Low similarity with the EmrE protein (Methyl viologen resistance protein C)(Ethidium resistance protein)in E.coli. Multidrug transporter. Confers resistance to a wide range of toxic compounds by removing them for the cells. The efflux is coupled to an influx of protons. Probably prevents the incorporation of methyl viologen into cells. Involved in ethidium bromide efflux. EMRE_ECOLI:P23895. InterPro:IPR000390; Smr. Pfam: PF00893; Multi_Drug_Res; 1. Signal peptide present. TMHelix: 4; High confidence in function and specificity. (118 aa)    
Predicted Functional Partners:
azo3592
Hypothetical protein predicted by Glimmer/Critica; Gene located in a gene cluster related to an unidentified cell surface polysaccharide.
 
     0.947
azo3591
Sugar or sugar nucleotide oxidoreductase; Family membership.
 
     0.939
azo3593
Hypothetical membrane protein. No good homology of the entire protein with the data bank. No domains predicted. No signal peptide. 1 TMH.
 
     0.933
azo3589
Glycosyltransferase; InterPro: Glycosyl transferase family 2. Slight similarity to dolicholphosphate mannosyltransferases,might therefore transfer a sugar moiety directly to a lipid carrier; Specificity unclear.
 
   
 0.890
azo3594
Glycosyltransferase; Putative glycosyl transferase sll0501 (EC 2.-.-.-); Specificity unclear.
 
   
 0.803
azo3588
Hypothetical membrane protein. No homology to the data bank. No domains predicted. no signal peptide. 9 TMHs; Conserved hypothetical protein.
       0.752
wbpV
Putative UDP-glucose 4-epimerase; 50%; High confidence in function and specificity.
     
 0.566
azo3585
Glycosyltransferase; Putative glycosyl transferase MJ1057 (EC 2.-.-.-). InterPro: Glycosyl transferase family 2; Family membership.
       0.566
fcl1
Putative GDP-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
     
 0.566
azo3582
Membrane protein involved in cell envelope biogenesis; Similar to proteins annotated as phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13) (UDP- MurNAc-pentapeptide phosphotransferase). First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity); Function unclear.
       0.562
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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