Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
azo3601Hypothetical protein PA4923. TREMBL:Q82UL5: 68% identity, 82% similarity InterPro:IPR005269; Cons_hypoth730. Pfam:PF03641; Lysine_decarbox; 1. TIGRFAMs:TIGR00730; Cons_hypoth730 bcl-2: Apoptosis regulator Non-secretory protein with signal peptide probability 0(Signal P predicted9 Absence of transmembrane helices (TMHHH predicted); Function unclear; Belongs to the LOG family. (240 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
       0.641
azo2060
Membrane-bound lytic murein transglycosylase D; Region start changed from 2259236 to 2259431 (-195 bases).
   
  0.611
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
   
 
  0.571
azo3602
Conserved hypothetical secreted protein. Homology to CV0777 of C.violaceum of 42% (trembl|Q7NZZ2(SRS)). No domains predicted. Signal peptide present. No TMH reported; Conserved hypothetical protein.
       0.538
azo3611
Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
    
  0.525
azo1019
Conserved hypothetical protein. Homology to CV2191 of C.violaceum of 64% (tremble:Q7NVZ9). Has PF02578,Uncharacterised ACR, YfiH family COG1496. InterPro;IPR003730. No signal peptide. No TMHs. TIGR00726: conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
  
  
 0.507
azo3603
Conserved hypothetical protein; G:T/U mismatch-specific DNA glycosylase.
       0.503
thrB
Probable homoserine kinase. Homology to thrB of M. flagellum of 51% (sprot|KHSE_METFL). CATALYTIC ACTIVITY: ATP + L-homoserine = ADP + O-phospho-L-homoserine. Pfam: Aminoglycoside phosphotransferase no signal peptide no TMHs; High confidence in function and specificity; Belongs to the pseudomonas-type ThrB family.
       0.503
azo1411
Conserved hypothetical ribonucleoside reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
 
    0.476
azo0857
38% PfkB.Family of carbohydrate kinases Pfam:PF00294; PfkB; 1; Specificity unclear.
    
 0.465
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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