| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ada | polA | azo2292 | azo3600 | Methylated-DNA--[protein]-cysteine S-methyltransferase (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) InterPro: Methylated-DNA--protein-cysteine methyltransferase; High confidence in function and specificity. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.711 |
| ada | tag | azo2292 | azo3621 | Methylated-DNA--[protein]-cysteine S-methyltransferase (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) InterPro: Methylated-DNA--protein-cysteine methyltransferase; High confidence in function and specificity. | DNA-3-methyladenine glycosylase I (EC 3.2.2.20) (3-methyladenine-DNA glycosylase I constitutive) (TAG I). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. InterPro: DNA-3-methyladenine glycosylase I; High confidence in function and specificity. | 0.517 |
| adhC | azo3624 | azo3623 | azo3624 | Alcohol dehydrogenase class III (Formaldehyde dehydrogenase (glutathione)). Homology to fdh of E. coli of 72% (trembl|Q59399) CLASS-III ADH IS REMARKABLY INEFFECTIVE IN OXIDIZING ETHANOL BUT IT READILY CATALYZES THE OXIDATION OF LONG-CHAIN PRIMARY ALOCHOLS AND THE OXIDATION OF S-(HYDROXYMETHYL) GLUTATHIONE (BY SIMILARITY). InterPro: Zinc-containing alcohol dehydrogenase superfamily (IPR002085) Zinc-containing alcohol dehydrogenase (IPR002328) Pfam: zinc-binding dehydrogenase Tigrfam: tdh: L-threonine 3-dehydrogenase. no signal peptide. 2 TMHs; High confidence in function and specificity. | Probable esterase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.999 |
| adhC | ptxR | azo3623 | azo3622 | Alcohol dehydrogenase class III (Formaldehyde dehydrogenase (glutathione)). Homology to fdh of E. coli of 72% (trembl|Q59399) CLASS-III ADH IS REMARKABLY INEFFECTIVE IN OXIDIZING ETHANOL BUT IT READILY CATALYZES THE OXIDATION OF LONG-CHAIN PRIMARY ALOCHOLS AND THE OXIDATION OF S-(HYDROXYMETHYL) GLUTATHIONE (BY SIMILARITY). InterPro: Zinc-containing alcohol dehydrogenase superfamily (IPR002085) Zinc-containing alcohol dehydrogenase (IPR002328) Pfam: zinc-binding dehydrogenase Tigrfam: tdh: L-threonine 3-dehydrogenase. no signal peptide. 2 TMHs; High confidence in function and specificity. | Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family. | 0.603 |
| adhC | tag | azo3623 | azo3621 | Alcohol dehydrogenase class III (Formaldehyde dehydrogenase (glutathione)). Homology to fdh of E. coli of 72% (trembl|Q59399) CLASS-III ADH IS REMARKABLY INEFFECTIVE IN OXIDIZING ETHANOL BUT IT READILY CATALYZES THE OXIDATION OF LONG-CHAIN PRIMARY ALOCHOLS AND THE OXIDATION OF S-(HYDROXYMETHYL) GLUTATHIONE (BY SIMILARITY). InterPro: Zinc-containing alcohol dehydrogenase superfamily (IPR002085) Zinc-containing alcohol dehydrogenase (IPR002328) Pfam: zinc-binding dehydrogenase Tigrfam: tdh: L-threonine 3-dehydrogenase. no signal peptide. 2 TMHs; High confidence in function and specificity. | DNA-3-methyladenine glycosylase I (EC 3.2.2.20) (3-methyladenine-DNA glycosylase I constitutive) (TAG I). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. InterPro: DNA-3-methyladenine glycosylase I; High confidence in function and specificity. | 0.499 |
| azo3620 | ptxR | azo3620 | azo3622 | Putative adenylate/ guanylate cyclase,; Function unclear. | Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family. | 0.442 |
| azo3620 | tag | azo3620 | azo3621 | Putative adenylate/ guanylate cyclase,; Function unclear. | DNA-3-methyladenine glycosylase I (EC 3.2.2.20) (3-methyladenine-DNA glycosylase I constitutive) (TAG I). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. InterPro: DNA-3-methyladenine glycosylase I; High confidence in function and specificity. | 0.484 |
| azo3624 | adhC | azo3624 | azo3623 | Probable esterase; Serine hydrolase involved in the detoxification of formaldehyde. | Alcohol dehydrogenase class III (Formaldehyde dehydrogenase (glutathione)). Homology to fdh of E. coli of 72% (trembl|Q59399) CLASS-III ADH IS REMARKABLY INEFFECTIVE IN OXIDIZING ETHANOL BUT IT READILY CATALYZES THE OXIDATION OF LONG-CHAIN PRIMARY ALOCHOLS AND THE OXIDATION OF S-(HYDROXYMETHYL) GLUTATHIONE (BY SIMILARITY). InterPro: Zinc-containing alcohol dehydrogenase superfamily (IPR002085) Zinc-containing alcohol dehydrogenase (IPR002328) Pfam: zinc-binding dehydrogenase Tigrfam: tdh: L-threonine 3-dehydrogenase. no signal peptide. 2 TMHs; High confidence in function and specificity. | 0.999 |
| azo3624 | ptxR | azo3624 | azo3622 | Probable esterase; Serine hydrolase involved in the detoxification of formaldehyde. | Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family. | 0.531 |
| azo3624 | tag | azo3624 | azo3621 | Probable esterase; Serine hydrolase involved in the detoxification of formaldehyde. | DNA-3-methyladenine glycosylase I (EC 3.2.2.20) (3-methyladenine-DNA glycosylase I constitutive) (TAG I). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. InterPro: DNA-3-methyladenine glycosylase I; High confidence in function and specificity. | 0.456 |
| polA | ada | azo3600 | azo2292 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Methylated-DNA--[protein]-cysteine S-methyltransferase (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) InterPro: Methylated-DNA--protein-cysteine methyltransferase; High confidence in function and specificity. | 0.711 |
| polA | tag | azo3600 | azo3621 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA-3-methyladenine glycosylase I (EC 3.2.2.20) (3-methyladenine-DNA glycosylase I constitutive) (TAG I). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. InterPro: DNA-3-methyladenine glycosylase I; High confidence in function and specificity. | 0.686 |
| ptxR | adhC | azo3622 | azo3623 | Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family. | Alcohol dehydrogenase class III (Formaldehyde dehydrogenase (glutathione)). Homology to fdh of E. coli of 72% (trembl|Q59399) CLASS-III ADH IS REMARKABLY INEFFECTIVE IN OXIDIZING ETHANOL BUT IT READILY CATALYZES THE OXIDATION OF LONG-CHAIN PRIMARY ALOCHOLS AND THE OXIDATION OF S-(HYDROXYMETHYL) GLUTATHIONE (BY SIMILARITY). InterPro: Zinc-containing alcohol dehydrogenase superfamily (IPR002085) Zinc-containing alcohol dehydrogenase (IPR002328) Pfam: zinc-binding dehydrogenase Tigrfam: tdh: L-threonine 3-dehydrogenase. no signal peptide. 2 TMHs; High confidence in function and specificity. | 0.603 |
| ptxR | azo3620 | azo3622 | azo3620 | Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family. | Putative adenylate/ guanylate cyclase,; Function unclear. | 0.442 |
| ptxR | azo3624 | azo3622 | azo3624 | Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family. | Probable esterase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.531 |
| ptxR | tag | azo3622 | azo3621 | Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family. | DNA-3-methyladenine glycosylase I (EC 3.2.2.20) (3-methyladenine-DNA glycosylase I constitutive) (TAG I). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. InterPro: DNA-3-methyladenine glycosylase I; High confidence in function and specificity. | 0.697 |
| tag | ada | azo3621 | azo2292 | DNA-3-methyladenine glycosylase I (EC 3.2.2.20) (3-methyladenine-DNA glycosylase I constitutive) (TAG I). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. InterPro: DNA-3-methyladenine glycosylase I; High confidence in function and specificity. | Methylated-DNA--[protein]-cysteine S-methyltransferase (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) InterPro: Methylated-DNA--protein-cysteine methyltransferase; High confidence in function and specificity. | 0.517 |
| tag | adhC | azo3621 | azo3623 | DNA-3-methyladenine glycosylase I (EC 3.2.2.20) (3-methyladenine-DNA glycosylase I constitutive) (TAG I). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. InterPro: DNA-3-methyladenine glycosylase I; High confidence in function and specificity. | Alcohol dehydrogenase class III (Formaldehyde dehydrogenase (glutathione)). Homology to fdh of E. coli of 72% (trembl|Q59399) CLASS-III ADH IS REMARKABLY INEFFECTIVE IN OXIDIZING ETHANOL BUT IT READILY CATALYZES THE OXIDATION OF LONG-CHAIN PRIMARY ALOCHOLS AND THE OXIDATION OF S-(HYDROXYMETHYL) GLUTATHIONE (BY SIMILARITY). InterPro: Zinc-containing alcohol dehydrogenase superfamily (IPR002085) Zinc-containing alcohol dehydrogenase (IPR002328) Pfam: zinc-binding dehydrogenase Tigrfam: tdh: L-threonine 3-dehydrogenase. no signal peptide. 2 TMHs; High confidence in function and specificity. | 0.499 |
| tag | azo3620 | azo3621 | azo3620 | DNA-3-methyladenine glycosylase I (EC 3.2.2.20) (3-methyladenine-DNA glycosylase I constitutive) (TAG I). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. InterPro: DNA-3-methyladenine glycosylase I; High confidence in function and specificity. | Putative adenylate/ guanylate cyclase,; Function unclear. | 0.484 |
| tag | azo3624 | azo3621 | azo3624 | DNA-3-methyladenine glycosylase I (EC 3.2.2.20) (3-methyladenine-DNA glycosylase I constitutive) (TAG I). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. InterPro: DNA-3-methyladenine glycosylase I; High confidence in function and specificity. | Probable esterase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.456 |