STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adhCAlcohol dehydrogenase class III (Formaldehyde dehydrogenase (glutathione)). Homology to fdh of E. coli of 72% (trembl|Q59399) CLASS-III ADH IS REMARKABLY INEFFECTIVE IN OXIDIZING ETHANOL BUT IT READILY CATALYZES THE OXIDATION OF LONG-CHAIN PRIMARY ALOCHOLS AND THE OXIDATION OF S-(HYDROXYMETHYL) GLUTATHIONE (BY SIMILARITY). InterPro: Zinc-containing alcohol dehydrogenase superfamily (IPR002085) Zinc-containing alcohol dehydrogenase (IPR002328) Pfam: zinc-binding dehydrogenase Tigrfam: tdh: L-threonine 3-dehydrogenase. no signal peptide. 2 TMHs; High confidence in function and specificity. (370 aa)    
Predicted Functional Partners:
azo3624
Probable esterase; Serine hydrolase involved in the detoxification of formaldehyde.
 0.999
adhA
Putative Alcohol dehydrogenase. Homology to adh-HT of B. stearothermophilus (sprot|ADH3_BACST) THERMOSTABLE AND THERMOPHILIC NAD(+)-DEPENDENT ALCOHOL DEHYDROGENASE. BEARS MAINLY AN ETHANOL-DEHYDROGENASE ACTIVITY. CATALYTIC ACTIVITY:An alcohol + NAD(+) = an aldehyde or ketone + NADH. COFACTOR: Binds 2 zinc ions per subunit (By similarity). Pfam: Zinc-binding dehydrogenase Tirgfam: tdh: L-threonine 3-dehydrogenase no signal peptide no TMHs; Family membership.
  
 
0.978
azo2700
Conserved hypothetical alcohol dehydrogenase. Homology to bp2820 of B. pertussis of 29% (TREMBL:Q7VV69). InterPro: Iron-containing alcohol dehydrogenase (IPR001670). Pfam: Iron-containing alcohol dehydrogenase. no signal peptide. no TMHs; Family membership.
    
 0.960
nagAa
Naphthalene 12-dioxygenase system ferredoxin--NAD(+) reductase component COMPONENT OF NAPHTHALENE DIOXYGENASE (NDO) MULTICOMPONENT ENZYME SYSTEM WHICH CATALYZES THE INCORPORATION OF BOTH ATOMS OF MOLECULAR OXYGEN INTO NAPHTHALENE TO FORM CIS- NAPHTHALENE DIHYDRODIOL. TRANSFERS ELECTRONS FROM FERREDOXIN (NDOA) TO NADH; High confidence in function and specificity.
  
 
 0.924
azo1971
Putative alcohol dehydrogenase; SPROT:ADH1_BACST:31% identity; 45% similarity Alcohol dehydrogenase (EC 1.1.1.1) (ADH-T). THERMOSTABLE NAD(+)-DEPENDENT ALCOHOL DEHYDROGENASE. an alcohol + nad(+) = an aldehyde or ketone + nadh. cofactor:binds 2 zinc ions per subunit (by similarity). InterPro: IPR002328; ADH_zinc. IPR002085:Adh_zn_family. Pfam:PF00107; ADH_zinc_N tdh: L-threonine 3-dehydrogenase; Specificity unclear.
  
 
0.865
aldA
Aldehyde dehydrogenase (NAD+). Homology to aldA of X. autotrophicus of 76% (trembl|O50203). Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no TMHs; High confidence in function and specificity.
 
 0.800
cumB
Cytidine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
 
  0.788
pcD
Probable piperideine-6-carboxylate dehydrogenase. Homology to pcd of F. lutescens of 53% (trembl|Q9F1U8) InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; Family membership.
 
 0.701
thmS1
Probable succinate semialdehyde dehydrogenase [NAD(P)+). Homology to thmS of Pseudonocardia sp. K1 of 55% (trembl|Q9F3V7). Is capable of oxidizing substrates using NADP as cofactor. InterPro: Aldehyde dehydrogenase family (IPR002086) Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; Family membership.
 
 0.691
cddD
Probable aldehyde dehydrogenase (NAD+). Homology to cddD of R. ruber SC1 of 59% (trembl|Q938F1) Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. Pfam: Aldehyde dehydrogenase family no TMHs no signal peptide; Family membership.
 
 0.691
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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