| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo3003 | cbl-2 | azo3003 | azo2327 | Conserved hypothetical transcriptional regulator,LysR family. Similar to SWISSPROT: sprot|NTCB_SYNP7 (18% Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2), nitrogen assimilation transcriptional activator NtcB) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; Family membership. | HTH-type transcriptional regulator cbl (Cys regulon transcriptional activator) Belongs to the LysR family of transcriptional regulators. THIS PROTEIN IS A POSITIVE REGULATOR OF GENE EXPRESSION FOR THE CYSTEINE REGULON. THE INDUCER FOR CYSB IS N-ACETYLSERINE (BY SIMILARITY). ribD_Cterm: riboflavin-specific deami 42% similarity to the HTH-type transcriptional regulator cbl, E. coli SWISSPROT:CBL_ECOLI IPR000847; HTH_LysR. IPR005119; LysR_subst. PF00126; HTH_1; 1. helix-turn-helix PF03466; LysR_substrate; 1. HTH reporting nucleic acid binding motif; High confidence in function and specificity. | 0.513 |
| azo3003 | crgA | azo3003 | azo3629 | Conserved hypothetical transcriptional regulator,LysR family. Similar to SWISSPROT: sprot|NTCB_SYNP7 (18% Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2), nitrogen assimilation transcriptional activator NtcB) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; Family membership. | Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. | 0.531 |
| azo3632 | crgA | azo3632 | azo3629 | ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q89UA9 (44% identity); TREMBL:Q92M72 (44% identity); SWISSPROT:Q9JI39 (32% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site mo [...] | Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. | 0.404 |
| azo3632 | yafB | azo3632 | azo3631 | ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q89UA9 (44% identity); TREMBL:Q92M72 (44% identity); SWISSPROT:Q9JI39 (32% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site mo [...] | 25-diketo-D-gluconic acid reductase B (EC 1.1.1.274) (25-DKG reductase B) (25-DKGR B) (25DKGR-B) (AKR5D). TREMBL:Q8Y090: 67% identity, 78% similarity. Catalyzes the reduction of 25-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG) (By similarity). subunit:monomer (by similarity). subcellular location:cytoplasmic (by similarity). 2-keto-l-gulonic acid is a key intermediate in the production of l-ascorbic acid (vitamin c). belongs to the aldo/keto reductase family InterPro:IPR001395; Aldo/ket_red. Pfam:PF00248; aldo_ket_red; 1. PRINTS PR00069; ALDKETRDTAS ribH: riboflavin sy [...] | 0.629 |
| azo3632 | ydeA | azo3632 | azo3630 | ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q89UA9 (44% identity); TREMBL:Q92M72 (44% identity); SWISSPROT:Q9JI39 (32% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site mo [...] | Sugar efflux transporter protein, involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites. Transports L-arabinose and to a lesser extent IPTG. Seems to contribute to the control of the arabinose regulon. 26% MFS.IPR005828; Sub_transporter. Belongs to major facilitator superfamily. SotB (TC 2.A.1.2) family. Signal peptide:present. TMHelix:12; Specificity unclear. | 0.554 |
| cbl-2 | azo3003 | azo2327 | azo3003 | HTH-type transcriptional regulator cbl (Cys regulon transcriptional activator) Belongs to the LysR family of transcriptional regulators. THIS PROTEIN IS A POSITIVE REGULATOR OF GENE EXPRESSION FOR THE CYSTEINE REGULON. THE INDUCER FOR CYSB IS N-ACETYLSERINE (BY SIMILARITY). ribD_Cterm: riboflavin-specific deami 42% similarity to the HTH-type transcriptional regulator cbl, E. coli SWISSPROT:CBL_ECOLI IPR000847; HTH_LysR. IPR005119; LysR_subst. PF00126; HTH_1; 1. helix-turn-helix PF03466; LysR_substrate; 1. HTH reporting nucleic acid binding motif; High confidence in function and specificity. | Conserved hypothetical transcriptional regulator,LysR family. Similar to SWISSPROT: sprot|NTCB_SYNP7 (18% Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2), nitrogen assimilation transcriptional activator NtcB) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; Family membership. | 0.513 |
| cbl-2 | crgA | azo2327 | azo3629 | HTH-type transcriptional regulator cbl (Cys regulon transcriptional activator) Belongs to the LysR family of transcriptional regulators. THIS PROTEIN IS A POSITIVE REGULATOR OF GENE EXPRESSION FOR THE CYSTEINE REGULON. THE INDUCER FOR CYSB IS N-ACETYLSERINE (BY SIMILARITY). ribD_Cterm: riboflavin-specific deami 42% similarity to the HTH-type transcriptional regulator cbl, E. coli SWISSPROT:CBL_ECOLI IPR000847; HTH_LysR. IPR005119; LysR_subst. PF00126; HTH_1; 1. helix-turn-helix PF03466; LysR_substrate; 1. HTH reporting nucleic acid binding motif; High confidence in function and specificity. | Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. | 0.474 |
| crgA | azo3003 | azo3629 | azo3003 | Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. | Conserved hypothetical transcriptional regulator,LysR family. Similar to SWISSPROT: sprot|NTCB_SYNP7 (18% Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2), nitrogen assimilation transcriptional activator NtcB) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; Family membership. | 0.531 |
| crgA | azo3632 | azo3629 | azo3632 | Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. | ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q89UA9 (44% identity); TREMBL:Q92M72 (44% identity); SWISSPROT:Q9JI39 (32% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site mo [...] | 0.404 |
| crgA | cbl-2 | azo3629 | azo2327 | Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. | HTH-type transcriptional regulator cbl (Cys regulon transcriptional activator) Belongs to the LysR family of transcriptional regulators. THIS PROTEIN IS A POSITIVE REGULATOR OF GENE EXPRESSION FOR THE CYSTEINE REGULON. THE INDUCER FOR CYSB IS N-ACETYLSERINE (BY SIMILARITY). ribD_Cterm: riboflavin-specific deami 42% similarity to the HTH-type transcriptional regulator cbl, E. coli SWISSPROT:CBL_ECOLI IPR000847; HTH_LysR. IPR005119; LysR_subst. PF00126; HTH_1; 1. helix-turn-helix PF03466; LysR_substrate; 1. HTH reporting nucleic acid binding motif; High confidence in function and specificity. | 0.474 |
| crgA | nodD | azo3629 | azo0679 | Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. | Probable nodulation protein,; Function unclear; Belongs to the LysR transcriptional regulatory family. | 0.408 |
| crgA | yafB | azo3629 | azo3631 | Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. | 25-diketo-D-gluconic acid reductase B (EC 1.1.1.274) (25-DKG reductase B) (25-DKGR B) (25DKGR-B) (AKR5D). TREMBL:Q8Y090: 67% identity, 78% similarity. Catalyzes the reduction of 25-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG) (By similarity). subunit:monomer (by similarity). subcellular location:cytoplasmic (by similarity). 2-keto-l-gulonic acid is a key intermediate in the production of l-ascorbic acid (vitamin c). belongs to the aldo/keto reductase family InterPro:IPR001395; Aldo/ket_red. Pfam:PF00248; aldo_ket_red; 1. PRINTS PR00069; ALDKETRDTAS ribH: riboflavin sy [...] | 0.582 |
| crgA | ydeA | azo3629 | azo3630 | Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. | Sugar efflux transporter protein, involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites. Transports L-arabinose and to a lesser extent IPTG. Seems to contribute to the control of the arabinose regulon. 26% MFS.IPR005828; Sub_transporter. Belongs to major facilitator superfamily. SotB (TC 2.A.1.2) family. Signal peptide:present. TMHelix:12; Specificity unclear. | 0.722 |
| nodD | crgA | azo0679 | azo3629 | Probable nodulation protein,; Function unclear; Belongs to the LysR transcriptional regulatory family. | Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. | 0.408 |
| yafB | azo3632 | azo3631 | azo3632 | 25-diketo-D-gluconic acid reductase B (EC 1.1.1.274) (25-DKG reductase B) (25-DKGR B) (25DKGR-B) (AKR5D). TREMBL:Q8Y090: 67% identity, 78% similarity. Catalyzes the reduction of 25-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG) (By similarity). subunit:monomer (by similarity). subcellular location:cytoplasmic (by similarity). 2-keto-l-gulonic acid is a key intermediate in the production of l-ascorbic acid (vitamin c). belongs to the aldo/keto reductase family InterPro:IPR001395; Aldo/ket_red. Pfam:PF00248; aldo_ket_red; 1. PRINTS PR00069; ALDKETRDTAS ribH: riboflavin sy [...] | ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q89UA9 (44% identity); TREMBL:Q92M72 (44% identity); SWISSPROT:Q9JI39 (32% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site mo [...] | 0.629 |
| yafB | crgA | azo3631 | azo3629 | 25-diketo-D-gluconic acid reductase B (EC 1.1.1.274) (25-DKG reductase B) (25-DKGR B) (25DKGR-B) (AKR5D). TREMBL:Q8Y090: 67% identity, 78% similarity. Catalyzes the reduction of 25-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG) (By similarity). subunit:monomer (by similarity). subcellular location:cytoplasmic (by similarity). 2-keto-l-gulonic acid is a key intermediate in the production of l-ascorbic acid (vitamin c). belongs to the aldo/keto reductase family InterPro:IPR001395; Aldo/ket_red. Pfam:PF00248; aldo_ket_red; 1. PRINTS PR00069; ALDKETRDTAS ribH: riboflavin sy [...] | Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. | 0.582 |
| yafB | ydeA | azo3631 | azo3630 | 25-diketo-D-gluconic acid reductase B (EC 1.1.1.274) (25-DKG reductase B) (25-DKGR B) (25DKGR-B) (AKR5D). TREMBL:Q8Y090: 67% identity, 78% similarity. Catalyzes the reduction of 25-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG) (By similarity). subunit:monomer (by similarity). subcellular location:cytoplasmic (by similarity). 2-keto-l-gulonic acid is a key intermediate in the production of l-ascorbic acid (vitamin c). belongs to the aldo/keto reductase family InterPro:IPR001395; Aldo/ket_red. Pfam:PF00248; aldo_ket_red; 1. PRINTS PR00069; ALDKETRDTAS ribH: riboflavin sy [...] | Sugar efflux transporter protein, involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites. Transports L-arabinose and to a lesser extent IPTG. Seems to contribute to the control of the arabinose regulon. 26% MFS.IPR005828; Sub_transporter. Belongs to major facilitator superfamily. SotB (TC 2.A.1.2) family. Signal peptide:present. TMHelix:12; Specificity unclear. | 0.869 |
| ydeA | azo3632 | azo3630 | azo3632 | Sugar efflux transporter protein, involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites. Transports L-arabinose and to a lesser extent IPTG. Seems to contribute to the control of the arabinose regulon. 26% MFS.IPR005828; Sub_transporter. Belongs to major facilitator superfamily. SotB (TC 2.A.1.2) family. Signal peptide:present. TMHelix:12; Specificity unclear. | ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Similar to TREMBL:Q89UA9 (44% identity); TREMBL:Q92M72 (44% identity); SWISSPROT:Q9JI39 (32% identity). InterPro (IPR003439): ABC transporter. InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site mo [...] | 0.554 |
| ydeA | crgA | azo3630 | azo3629 | Sugar efflux transporter protein, involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites. Transports L-arabinose and to a lesser extent IPTG. Seems to contribute to the control of the arabinose regulon. 26% MFS.IPR005828; Sub_transporter. Belongs to major facilitator superfamily. SotB (TC 2.A.1.2) family. Signal peptide:present. TMHelix:12; Specificity unclear. | Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family. | 0.722 |
| ydeA | yafB | azo3630 | azo3631 | Sugar efflux transporter protein, involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites. Transports L-arabinose and to a lesser extent IPTG. Seems to contribute to the control of the arabinose regulon. 26% MFS.IPR005828; Sub_transporter. Belongs to major facilitator superfamily. SotB (TC 2.A.1.2) family. Signal peptide:present. TMHelix:12; Specificity unclear. | 25-diketo-D-gluconic acid reductase B (EC 1.1.1.274) (25-DKG reductase B) (25-DKGR B) (25DKGR-B) (AKR5D). TREMBL:Q8Y090: 67% identity, 78% similarity. Catalyzes the reduction of 25-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG) (By similarity). subunit:monomer (by similarity). subcellular location:cytoplasmic (by similarity). 2-keto-l-gulonic acid is a key intermediate in the production of l-ascorbic acid (vitamin c). belongs to the aldo/keto reductase family InterPro:IPR001395; Aldo/ket_red. Pfam:PF00248; aldo_ket_red; 1. PRINTS PR00069; ALDKETRDTAS ribH: riboflavin sy [...] | 0.869 |