STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3671Conserved hypothetical protein. Homology to BPP4351 of B.parapertussis of 38% (trembl:Q7W2Q3). No domains predicted. No TMHs. No signal peptide. (111 aa)    
Predicted Functional Partners:
hpt
Hypoxanthine phosphoribosyltransferase (Hypoxanthine-guanine phosphoribosyltransferase. (HGPRTase) (IMP pyrophosphorylase) (IMP diphosphorylase) (Transphosphoribosidase) (Guanine phosphoribosyltransferase); Function unclear.
       0.768
azo3606
Conserved hypothetical protein. Homology to ne1472 of N. europaea of 33% (trembl|Q82UL2(SRS)). No domains predicted. No signal peptide. 6 TMHs.
  
     0.672
rlpB
Putative lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.
  
     0.616
azo3300
Conserved hypothetical membrane protein, 73% similarity to TrEMBL;Q7WE10,Putative membrane protein [BB4828] [Bordetella bronchiseptica(Alcaligenes bronchisepticus). no signal peptide. 1 TMHs.
  
     0.614
azo3668
Conserved hypothetical membrane protein. Homology to rs05101 R. solanacearum of 36% (trembl|Q8Y1D8(SRS)). No domains predicted. No signal peptide. 2 TMHs; Conserved hypothetical protein.
 
     0.594
azo3231
Conserved hypothetical membrane protein. Homology to ebA4352 of Azoarcus sp. EbN1 of 31% (gnl|keqq|eba:ebA4352(KEGG)). Has PF04401, Protein of unknown function (DUF540); IPR007496 DUF540; Uncharacterised bacterial integral membrane protein,possibly involved in cysteine biosynthesis. Speculated to be involved in sulphate transport. no signal peptide. 6 TMHs; Conserved hypothetical protein.
  
     0.557
azo0095
DNA topoisomerase I (EC 5.99.1.2) (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase). THE REACTION CATALYZED BY TOPOISOMERASES LEADS TO THE CONVERSION OF ONE TOPOLOGICAL ISOMER OF DNA TO ANOTHER. MAY PLAY AN IMPORTANT ROLE IN EITHER THE MAINTENANCE OF OR EXPRESSION FROM THE VIRULENCE PLASMID. ITS INFLUENCE ON EXPRESSION COULD BE SPECIFIC TUNING LOCAL SUPERHELICITY OR MORE GENERALLY MODIFYING THE SUPERHELICITY OF THE ENTIRE PLASMID IN RESPONSE TO ENVIRONMENTAL STIMULI THUS COULD BE A FUNDAMENTAL FACTOR INVOLVED IN VIRULENCE. InterPro: Prokaryotic DNA topoisomerase I; High [...]
  
     0.547
azo3974
Conserved hypothetical protein. Homology to bb4936 of B. bronchiseptica of 36% (trembl|Q7WDQ2). no domains predicted. no signal peptide. no TMHs.
  
    0.547
azo3727
Conserved hypothetical secreted protein. Homology to ebA3180 of Azoarcus sp. EbN1 of 57% (gi|56477224|ref|YP_158813.1|(NBCI ENTREZ)). No domains predicted Signal Peptide present. No TMH reported present; Conserved hypothetical protein.
  
     0.526
azo0152
Conserved hypothetical membrane protein. Homology to BB4612 of Bordetella bronchiseptica of 37% (trembl|Q7WEM2(SRS)). No domains predicted. signal peptide 3 TMHs; Conserved hypothetical protein.
  
     0.520
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.