STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3682Putative cyclase; Beta-lactamase II precursor (EC 3.5.2.6) (Penicillinase) (Cephalosporinase). Can hydrolyze carbapenem compounds. InterPro:IPR001279-Metallo-beta-lactamase superfamily TREMBL:Q8XRX8-72% identity TREMBL:Q7VUG6- 62% Pfam:PF00753-LactamaseB, Ribosomal proteinS6e,ThiC family TIGRFAM:TIGR00010- TatD/hisF family TMHMM predicted transmembrane helix. mobB: molybdopterin-guanine dinucleotide; High confidence in function and specificity. (321 aa)    
Predicted Functional Partners:
mhpA
Putative oxygenase. 3-(3-hydroxy-phenyl)propionate hydroxylase (EC 1.14.13.-), InterPro: Aromatic-ring hydroxylase (flavoprotein monooxygenase); Specificity unclear.
 
    0.917
azo3680
Conserved hypothetical protein. Homology to RS01748 of R.solanacearum of 59% (trembl:Q8XRY0). No domains predicted. No TMHs. No signal peptide.
 
     0.901
gylR
Putative transcriptional regulator iclR-family,; Family membership.
 
     0.763
azo3679
Glyoxalase-family protein; Glyoxalase I (lactoylglutathione lyase) catalyzes the first step of the glyoxal pathway. Similar to trembl|Q89SS0 (63%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Family membership.
 
  
  0.668
azo2279
Conserved hypothetical protein. Homology to Avin02000067 of Azotobacter vinelandii of 50% (gi|23105742|ref|ZP_00092196.1|(NBCI ENTREZ)). InterPro: Ankyrin-repeat. The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids.The ankyrin fold appears to be defined by its structure rather than its function since there is no specific sequence or structure which is universally recognised by it. The conserved fold of the ankyrin repeat unit is known from several crystal and solution structures [...]
   
 0.608
nagL2
Probable maleylpyruvate isomerase. Homology to nagL of Ralstonia spU of 50% (trembl|O86043) NagL is a reduced glutathione-dependent maleylpyruvate isomerase catalyzing the isomerization of maleypyruvate to fumarylpyruvate. InterPro: Glutathione S-transferase N terminus (IPR004045), Glutathione S-transferase C terminus (IPR004046) Pfam: Glutathione S-transferase, N-terminal domaine no signal peptide no TMHs; High confidence in function and specificity.
 
 
   0.586
azo3678
This family consists of fumarylacetoacetate (FAA) hydrolase, or fumarylacetoacetate hydrolase (FAH) and it also includes HHDD isomerase/OPET decarboxylase from E. coli strain W. Similar to TREMBL:Q9KSB3 (67% identity); TREMBL:Q92LT4 (67% identity); TREMBL:Q8EGD4 (61% identity). Pfam (PF01557): Fumarylacetoacetate (FAA) hydrolase family; Family membership.
 
     0.580
ooxA
Putative opine oxidase subunit A. Homology to ooxA of A. tumefaciens of 37% (sprot|OOXA_AGRT4). OXIDATIVE CLEAVAGE OF OCTOPINE INTO L-ARGININE AND PYRUVATE (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327), NAD-bining site (IPR000205) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership.
 
  
 0.562
azo1777
Hypothetical LuxR-family transcriptional regulator. Similarity to other known proteins (dctR or narP or esaR) only in the domain part. Pfam: PF00196 Bacterial regulatory proteins, luxR family. HTH reporting nucleic acid binding motif. The 'helix-turn-helix' DNA-binding motif of this protein is located in the C-terminal section of the sequence; Conserved hypothetical protein.
    
   0.521
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
 
 0.510
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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