STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3692Putative N-acetyltransferase,51% Identity to TrEMBl;Q7WQB1,54% Identity to TrEMBL;Q63LT2,Q7WCA7. Has PF00583, Acetyltransferase (GNAT) family;IPR000182,GCN5acetyl_trans; This family contains proteins with N-acetyltransferase functions. Histone acetylation is carried out by a class of enzymes known as histone acetyltransferases (HATs), which catalyze the transfer of an acetyl group from acetyl-CoA to the lysine E -amino groups on the N-terminal tails of histones. Early indication that HATs were involved in transcription came from the observation that in actively transcribed regions of c [...] (188 aa)    
Predicted Functional Partners:
azo3693
Similar to hypothetical integral membrane transport protein yidY (MFS family). Signal peptide containing non secretory protein. With 12 putative transmembrane helices. General transport of carbohydrates, amino acids, and other small molecules; Conserved hypothetical protein.
       0.800
metH
Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.683
ureA
Urease gamma subunit. Homology to ureA of S. meliloti of 71% (sprot|URE3_RHIME) Urease (urea amidohydrolase, EC: 3.5.1.5) catalyses the hydrolysis of urea to form ammonia and carbamate. The enzyme consists of three structural domains: an alpha subunit (with the C-terminal two-thirds representing the catalytic domain), a beta subunit and a gamma subunit. InterPro: Urease gamma subunit (IPR002026) Pfam: urease, gamma subunit Tigrfam: urease_gam: urease gamma subunit no signal peptide no TMHs; High confidence in function and specificity.
  
    0.579
ureD
Putative urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
  
    0.565
metG
MetG protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
  0.554
azo3691
Putative methyl-accepting chemotaxis protein,Chmtaxis_transd. IPR003660; HAMP. Pfam: PF00672; HAMP. PF00015; MCPsignal. SMART: SM00304; HAMP. SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices; Family membership.
       0.533
azo3694
Hypothetical secreted protein. No good homology to the data bank. Has Signal Peptide.
       0.533
hisH
Histidine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
    
  0.455
hisF
Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
    
  0.454
azo3710
Conserved hypothetical transferase. Homology to the IAA acetyltransferase of A. brasilense of 37% (sprot|IAAT_AZOBR). The IAA acetyltransferase participates in the tryptophan-dependent indole-3-acetic acid production, which is a phytohormone released by A.brasilense. Interpro: GCN5-related N-acetyltransferase (IPR000182). Pfam: Acetyltransferase (GNAT) family. no signal peptide. no TMHs; Conserved hypothetical protein.
 
  
 0.437
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (22%) [HD]