STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3693Similar to hypothetical integral membrane transport protein yidY (MFS family). Signal peptide containing non secretory protein. With 12 putative transmembrane helices. General transport of carbohydrates, amino acids, and other small molecules; Conserved hypothetical protein. (408 aa)    
Predicted Functional Partners:
azo3692
Putative N-acetyltransferase,51% Identity to TrEMBl;Q7WQB1,54% Identity to TrEMBL;Q63LT2,Q7WCA7. Has PF00583, Acetyltransferase (GNAT) family;IPR000182,GCN5acetyl_trans; This family contains proteins with N-acetyltransferase functions. Histone acetylation is carried out by a class of enzymes known as histone acetyltransferases (HATs), which catalyze the transfer of an acetyl group from acetyl-CoA to the lysine E -amino groups on the N-terminal tails of histones. Early indication that HATs were involved in transcription came from the observation that in actively transcribed regions of c [...]
       0.800
azo3691
Putative methyl-accepting chemotaxis protein,Chmtaxis_transd. IPR003660; HAMP. Pfam: PF00672; HAMP. PF00015; MCPsignal. SMART: SM00304; HAMP. SM00283; MA. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices; Family membership.
       0.533
azo3694
Hypothetical secreted protein. No good homology to the data bank. Has Signal Peptide.
       0.533
pheA
Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity.
     
 0.482
pabB
Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear.
   
 
 0.453
fsr
A gene conferring resistance to fosmidomycin (Fs) encode a putative polypeptide of 406 amino acids (aa) with a molecular weight of 43303 in E.coli. 23% similarity to B. japonicum fsr. A comparison between the aa sequence of Fsr and sequences in a protein database revealed 18% homology to the bacterial drug-export proteins that mediate resistance to tetracycline and chloramphenicol. Hydropathy analysis of the Fsr protein revealed twelve putative transmembrane segments. Fsr does not have any direct effect on the biosynthesis of isoprenoid in E. coli, and that the mechanism for FsR involv [...]
  
  
 0.431
aas
AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Ac [...]
    
 0.428
repA
Probable replicase protein,functional similarity(67%) to TrEMBL Q6I6A6,PF04796;IPR006881 Has pfam04796, RepA_C domain, Plasmid encoded RepA protein. Family of plasmid encoded proteins involved in plasmid replication. The role of RepA in the replication process is not clearly understood. No Signal peptide or TMH are reported to be present; Specificity unclear.
  
     0.409
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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