Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo3703Conserved hypothetical membrane protein. Homology to PM2013 of P. multocida of 44% (tremble:Q9CJJ4). probable signal peptide. probable 2 TMHS; Conserved hypothetical protein. (153 aa)    
Predicted Functional Partners:
metH
Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.877
napG
Probable ferredoxin-type protein napG. Homology to napG of E. coli of 57% (sprot|NAPG_ECOLI). Involved in electron transfer in a wide variety of metabolic reactions. InterPro: MauM/NapG family ferredoxin-type protein (IPR004494); 7 Fe ferredoxin (IPR000813); 4Fe-4S ferredoxin; iron-sulfur binding domain (IPR001450) Pfam: 4Fe-4S binding domain Tigrfam: mauM_napG: MauM/NapG family ferredoxin-type protein no signal peptide no TMHs; High confidence in function and specificity.
     
  0.602
sseA
SseA: putative thiosulfate sulfurtransferase (rhodanese-like protein) [EC:2.8.1.1]. This protein transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity (130-fold lower). Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity. Probable 3-mercaptopyruvate sulfurtransferase (EC 2.8.1.2) (Rhodanese- like protein) (MST). InterPro: Rhodanese/cdc25 fold; High confidence in function and specificity.
    
  0.562
azo3704
Hypothetical membrane protein. No homology of the entire protein to the data bank. Has PF05875;Alkaline phytoceramidase (aPHC):This family consists of several eukaryotic Alkaline phytoceramidase (aPHC) sequences. Ceramidases are enzymes involved in regulating cellular levels of ceramides, sphingoid bases, and their phosphates. Alkaline phytoceramidase (aPHC) is responsible for the hydrolysis of phytoceramide. No signal peptide. 6 TMHs.
       0.546
azo3817
Conserved hypothetical protein. Homology to slr1189 of Synechocystis of 43% (trembl|P74718). Pfam: Homocystein S-transferase. no signal peptide. no TMHs.
    
  0.513
metF
5,10-methylenetetrahydrofolate reductase (FADH2; 510-methylenetetrahydrofolate reductase InterPro: Methylenetetrahydrofolate reductase fadh2: 510-methylenetetrahydrofolate reductase; High confidence in function and specificity; Belongs to the methylenetetrahydrofolate reductase family.
     
  0.505
acyH
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
  0.505
metZ
Cys/Met metabolism pyridoxal-phosphate-dependent enzyme; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
     
  0.505
azo1737
Conserved hypothetical membrane protein. Homology to ebA6987 of Azoarcus sp. EbN1 of 62% (gnl|keqq|eba:ebA6987(KEGG)). no domains predicted. no signal peptide. 4 TMHs; Conserved hypothetical protein.
     
  0.505
azo3380
Conserved hypothetical transaminase; Region start changed from 3714581 to 3714479 (102 bases).
     
  0.505
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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