STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gapRPutative AraC family transcriptional regulator,; High confidence in function and specificity. (354 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.707
azo0040
Putative AraC-family transcriptional regulator,; Family membership.
  
   0.692
azo3706
Conserved hypothetical protein; Similar to TREMBL:Q89RW7 (50% identity,64% similarity); TREMBL:Q88IS2 (49% identity). InterPro (IPR000051); SAM (and some other nucleotide) binding motif.
 
     0.670
azo0206
Putative AraC-family transcriptional regulator,; Family membership.
  
   0.663
pobR1
pobR. Transcriptional regulator AraC family. InterPro: AraC type helix-turn-helix pdxH: pyridoxamine 5-phosphate oxidase; Function unclear.
 
 
 0.534
rpoS
Putative RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
   
 
 0.507
rpoH
RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
   
 
 0.507
azo3019
Putative AraC family,transcriptional regulator, 28% Identity to TrEMBL;Q62GH5,Q6QEJ0,Q9HWT4 Has SMART;SM00342,HTH_ARAC, helix_turn_helix, arabinose operon control protein;IPR000005; Many bacterial transcription regulation proteins bind DNA through a 'helix-turn-helix' (HTH) motif. One major subfamily of these proteins is related to the arabinose operon regulatory protein AraC. Except for celD all of these proteins seem to be positive transcriptional factors.Although the sequences belonging to this family differ somewhat in length, in nearly every case the HTH motif is situated towards [...]
  
   0.463
azo2654
Lactoylglutathione lyase; Glyoxalase family protein, 54% identity (67% similarity) to TrEMBL;Q88HB6. Has PF00903,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;IPR004360, Gly_bleo_diox: Glyoxalase I catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid. The bacterial and yeast enzymes are monomeric while the mammalian one is homodimeric. The sequence of glyoxalase I is well conserved. This domain is found in other related proteins including the Bleomycin resistance protein and dioxygenases eg. 4-hydroxyp [...]
 
    0.434
azo0011
The short-chain dehydrogenases/reductases family is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases, similarity to SWISSPROT:P37959 (35% identity); TREMBL:Q930L8 (44% identity); TREMBL:Q9I3W5 (41% identity). Pfam (PF00106): Short chain dehydrogenase. InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase; Specificity unclear.
  
     0.432
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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