Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
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gapRPutative AraC family transcriptional regulator,; High confidence in function and specificity. (354 aa)    
Predicted Functional Partners:
azo0040
Putative AraC-family transcriptional regulator,; Family membership.
  
 
 0.687
azo3706
Conserved hypothetical protein; Similar to TREMBL:Q89RW7 (50% identity,64% similarity); TREMBL:Q88IS2 (49% identity). InterPro (IPR000051); SAM (and some other nucleotide) binding motif.
 
     0.669
azo0206
Putative AraC-family transcriptional regulator,; Family membership.
  
 
 0.659
pobR1
pobR. Transcriptional regulator AraC family. InterPro: AraC type helix-turn-helix pdxH: pyridoxamine 5-phosphate oxidase; Function unclear.
 
 
 0.566
rpoD
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.563
azo3019
Putative AraC family,transcriptional regulator, 28% Identity to TrEMBL;Q62GH5,Q6QEJ0,Q9HWT4 Has SMART;SM00342,HTH_ARAC, helix_turn_helix, arabinose operon control protein;IPR000005; Many bacterial transcription regulation proteins bind DNA through a 'helix-turn-helix' (HTH) motif. One major subfamily of these proteins is related to the arabinose operon regulatory protein AraC. Except for celD all of these proteins seem to be positive transcriptional factors.Although the sequences belonging to this family differ somewhat in length, in nearly every case the HTH motif is situated towards [...]
  
 
 0.456
azo2654
Lactoylglutathione lyase; Glyoxalase family protein, 54% identity (67% similarity) to TrEMBL;Q88HB6. Has PF00903,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;IPR004360, Gly_bleo_diox: Glyoxalase I catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by glyoxalase II to lactic acid. The bacterial and yeast enzymes are monomeric while the mammalian one is homodimeric. The sequence of glyoxalase I is well conserved. This domain is found in other related proteins including the Bleomycin resistance protein and dioxygenases eg. 4-hydroxyp [...]
 
    0.448
azo0011
The short-chain dehydrogenases/reductases family is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases, similarity to SWISSPROT:P37959 (35% identity); TREMBL:Q930L8 (44% identity); TREMBL:Q9I3W5 (41% identity). Pfam (PF00106): Short chain dehydrogenase. InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase; Specificity unclear.
  
     0.432
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
   0.408
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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