STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3724Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. (254 aa)    
Predicted Functional Partners:
azo3725
Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership.
     0.994
xerC
Site-specific recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
 
 
 
 0.737
xerD
Integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
  
     0.611
comF
Hypothetical protein yhgH. Members of PRT family are catalytic and regulatory proteins involved in nucleotide synthesis and salvage. The name PRT comes from phosphoribosyltransferase enzymes, which carry out phosphoryl transfer reactions on PRPP, an activated form of ribose-5-phosphate SPROT:P46846: 33% identity, 51% similarity InterPro; IPR000836; PRtransferase. Pfam; PF00156; Pribosyltran; 1 Absence of Signal peptide and Transmembrane helices PPR: pentatricopeptide repeat domain; High confidence in function and specificity.
   
    0.516
azo3723
Hypothetical protein predicted by Glimmer/Critica. no homology to the data bank. no domains predicted. no signal peptide. no TMHs.
       0.496
tyrA
Prephenate dehydrogenases are involved in tyrosine biosynthesis. Similar to trembl|Q7NSL5 (54%) and to trembl|Q82XD9 (47%). Pfam: PDH, Prephenate dehydrogenase. TMHMM reporting one Tmhelix. SignalP reporting Signal peptide; Specificity unclear.
  
    0.484
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.413
azo3722
Hypothetical protein, Has very weak or no homologs in the Database. Has No domains, repeats, motifs or features predicted above threshold score.
       0.412
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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