| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo3724 | azo3725 | azo3724 | azo3725 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | 0.994 |
| azo3724 | azo3948 | azo3724 | azo3948 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | Putative DNA-directed polymerase III; Excinuclease cho (EC 3.1.25.-) (Endonuclease cho) (UvrC homolog protein). Incises the DNA at the 3 side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than uvrC. Not able to incise the 5 site of a lesion. When a lesion remains because uvrC is not able to induce the 3 incision cho incises the DNA. Then uvrC makes the 5 incision. The combined action of cho and uvrC broadens the substrate range of nucleotide excision repair (By similarity); Specificity unclear. | 0.772 |
| azo3724 | rpsC | azo3724 | azo3411 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.777 |
| azo3724 | rpsI | azo3724 | azo2759 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | 30S ribosomal protein S9; High confidence in function and specificity; Belongs to the universal ribosomal protein uS9 family. | 0.785 |
| azo3724 | rpsO | azo3724 | azo2104 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | 30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.784 |
| azo3724 | rpsQ | azo3724 | azo3408 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.777 |
| azo3724 | rpsR | azo3724 | azo0720 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.780 |
| azo3724 | ruvB | azo3724 | azo0601 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.752 |
| azo3724 | uvrB | azo3724 | azo1611 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.748 |
| azo3724 | xerC | azo3724 | azo0596 | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | Site-specific recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.923 |
| azo3725 | azo3724 | azo3725 | azo3724 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | Truncated integrase/recombinase, probably Integrase/recombinase protein. 58% Identity to SProt;P62591,P62592. Has PF00589, Phage integrase family; IPR002104, Phage_integrase; Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase (P06956) are Arg-173, His-289, Arg-292 and Tyr-324. Homology only to the N-terminus. | 0.994 |
| azo3725 | azo3948 | azo3725 | azo3948 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | Putative DNA-directed polymerase III; Excinuclease cho (EC 3.1.25.-) (Endonuclease cho) (UvrC homolog protein). Incises the DNA at the 3 side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than uvrC. Not able to incise the 5 site of a lesion. When a lesion remains because uvrC is not able to induce the 3 incision cho incises the DNA. Then uvrC makes the 5 incision. The combined action of cho and uvrC broadens the substrate range of nucleotide excision repair (By similarity); Specificity unclear. | 0.772 |
| azo3725 | rpsC | azo3725 | azo3411 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.777 |
| azo3725 | rpsI | azo3725 | azo2759 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | 30S ribosomal protein S9; High confidence in function and specificity; Belongs to the universal ribosomal protein uS9 family. | 0.785 |
| azo3725 | rpsO | azo3725 | azo2104 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | 30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.784 |
| azo3725 | rpsQ | azo3725 | azo3408 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.777 |
| azo3725 | rpsR | azo3725 | azo0720 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.780 |
| azo3725 | ruvB | azo3725 | azo0601 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.785 |
| azo3725 | uvrB | azo3725 | azo1611 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.748 |
| azo3725 | xerC | azo3725 | azo0596 | Putative truncated integrase/recombinase (E2 protein). PUTATIVE INTEGRASE BELIEVED TO BE INVOLVED IN INSERTIONS OF ANTIBIOTIC RESISTANCE GENES INTO PLASMIDS AND TRANSPOSONS. Homology only to the C-terminus; Family membership. | Site-specific recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.811 |
