STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3728Probable lipoprotein, 58% similarity to TrEMBL:Q8XWT8 PROBABLE LIPOPROTEIN [RS01163] [Ralstonia solanacearum (Pseudomonas solanacearum)]. Has PF04355:IPR007450:SmpA / OmlA family;Lipoprotein Bacterial outer membrane lipoprotein, possibly involved in in maintaining the structural integrity of the cell envelope [1]. Lipid attachment site is a conserved N terminal cysteine residue. Sometimes found adjacent to the OmpA domain (OmpA). Signal peptide present. NO TMH reported present; Family membership. (162 aa)    
Predicted Functional Partners:
azo3727
Conserved hypothetical secreted protein. Homology to ebA3180 of Azoarcus sp. EbN1 of 57% (gi|56477224|ref|YP_158813.1|(NBCI ENTREZ)). No domains predicted Signal Peptide present. No TMH reported present; Conserved hypothetical protein.
 
    
0.828
comL
Probable competence lipoprotein precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
   
 
 0.782
oma
Outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
    
 
 0.781
nlpB
Putative lipoprotein. Homology to nlpB of E. coli of 20% (sprot|NLPB_ECOLI) This family consists of a number of bacterial lipoproteins often known as NlpB or DapX. This lipoprotein is detected in outer membrane vesicles in Escherichia coli and appears to be nonessential. Pfam: NlpB/DapX lipoprotein singal peptide no TMHs; Family membership.
  
 
 0.765
azo0152
Conserved hypothetical membrane protein. Homology to BB4612 of Bordetella bronchiseptica of 37% (trembl|Q7WEM2(SRS)). No domains predicted. signal peptide 3 TMHs; Conserved hypothetical protein.
  
     0.757
azo0364
Conserved hypothtical membrane protein. Homology to rc03284 of R. solanacearum of 35% (trembl|Q8Y2L8(SRS) Has a weak hit to PF04892(IPR006976;vanZ)in Smart:This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases. VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te). Analysis of cytoplasmic peptidoglycan precursors, accumulated in the presence of ramoplanin,showed that VanZ-mediated Te resistance does not involve incorporation of a substituent of D-alanine into the peptidoglycan precursors. no signal p [...]
  
     0.703
azo0398
Putative beta lactamase; Probable Hypothetical protein ycbL. TREMBL:Q8Y2S7-43% identity,57% similarity. TIGRFAM:2A0115-Benzoate transport proteins belong to this group. Benzyl alcohol,benzaldehyde, benzoate, and anthranilate are metabolized via catechol, cis,cis-muconate, and the beta-ketoadipate pathway in some bacteria InterPro: Metallo-beta-lactamase superfamily Pfam:Metallo Beta lactamase superfamily, Phage lysozyme TMHMM predicted transmembrane heleces ftsZ: cell division protein FtsZ; Function unclear.
  
     0.671
azo1694
Conserved hypothetical protein. Homology to ebA6519 of Azoarcus sp. EbN1 of 44% (gnl|keqq|eba:ebA6519(KEGG)). no domains predicted. signal peptide present. no TMHs.
  
    0.646
citE
Probable Citrate lyase beta chain(EC 4.1.3.6)(Citrase)(Citryl-CoA lyase subunit)(EC 4.1.3.34). In citrate-utilising prokaryotes, citrate lyase cleaves intracellular citrate into acetate and oxaloacetate, and is organised as a functional complex consisting of alpha,beta, and gamma subunits.The alpha subunit substitutes citryl for the acetyl group to form citryl-S-ACP. The beta subunit completes the reaction by cleaving the citryl to yield oxaloacetate and (regenerated) acetyl-S-ACP. Similar to the CitE protein from L.mesenteroides where is part of a gene cluster citCDEFG. SWISSPROT:CILB [...]
  
     0.622
fimV2
Putative type 4 pilus biogenesis; In Pseudomonas aeruginosa, FimV is probable involved in remodelling of the peptidoglycan layer to enable assembly of the type IV fimbrial structure and machinery. And it is also required for twitching motility. Similar to trembl|O87015 (26%). Pfam (PF05489): Phage Tail Protein X SignalP reporting Signal peptide; Function unclear.
  
     0.617
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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