Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo3736Conserved hypothetical protein. Homology to rsc0338 of R. solanacearum of 64% (trembl|Q8Y2J7). Probable Mg(2+) chelatase family protein. InterPro: Mg chelatase-related protein (IPR004482); MCM family (IPR001208); AAA ATPase superfamily (IPR003593); Magnesium chalatase, chlI subunit (IPR000523); TypeI antifreeze protein (IPR000104). no signal peptide. no TMHs. TIGR00368: Mg chelatase-related protein; Family membership. (499 aa)    
Predicted Functional Partners:
comF
Hypothetical protein yhgH. Members of PRT family are catalytic and regulatory proteins involved in nucleotide synthesis and salvage. The name PRT comes from phosphoribosyltransferase enzymes, which carry out phosphoryl transfer reactions on PRPP, an activated form of ribose-5-phosphate SPROT:P46846: 33% identity, 51% similarity InterPro; IPR000836; PRtransferase. Pfam; PF00156; Pribosyltran; 1 Absence of Signal peptide and Transmembrane helices PPR: pentatricopeptide repeat domain; High confidence in function and specificity.
 
  
 0.886
drpA
Putative DNA processing protein DrpA (Smf protein). Homology to drpA of H. influcenzae The SMF family (DNA processing chain A, dprA) are a group of bacterial proteins. In Helicobacter pylori, dprA is required for natural chromosomal and plasmid transformation InterPro: SMF family Tigerfam: dprA: DNA processing protein DprA,putative Pfam SMF family no signal peptide no TMHs; Family membership.
 
 
 0.843
azo0871
Conserved hypothetical protein. Homology to pa4424 of P. aeruginosa of 44% (pir|H83091). Pfam: Uncharacterised protein family UPF0102 (PF02021). Interpro: Protein of unkown function UPF0102 (IPR003509). no signal peptide. no TMHs.
 
  
 0.766
bcr2
Bicyclomycin resistance protein homolog. Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase (By similarity). InterPro: General carbohydrate, amino acid, and divalent cation transport. Occurence of signal peptide and 12 transmembrane helices. Presence of DUF domains and Cation transport ATPase C-terminus domains. 35% identity and 47% similarity to bcr from X.axonopodis. Probably it is a copy of bcr1 in Azoarcus BH72 genome; Conserved hypothetical protein.
       0.702
comA
Putative DNA uptake/competence protein; Competence protein comA. Essential for natural transformation. Could be a transporter involved in DNA uptake. InterPro: DNA internalization-related competence protein ComEC/Rec2 function: transporter activity TREMBL:Q82SD2: 38% identity,50% similarity. InterPro:IPR001279; Blactmase-like. IPR004477; ComEC_N-term. IPR004797; ComEC_Rec2. Pfam PF03772; Competence; 1. PF00753; Lactamase_B; 1. TIGRFAMs:TIGR00360; ComEC_N-term; 1. TIGR00361; ComEC_Rec2; ComEC_Rec2: DNA internalization-relate TMHMM predicted 8 transmembrane helices; High confidence in fu [...]
 
  
 0.692
ruvC
Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
   
 0.671
azo2638
Conserved hypothetical ATPase. Homology to rsc1961 of R. solanacearum of 37% (trembl|Q8XY02). Pfam: Atpase familly associated with various cellular activities (domaine 1 from 300 aa to 499 aa, domaine 2 from 543 to 723 aa). no signal peptide. no TMHs; Conserved hypothetical protein.
     
  0.641
azo3791
Conserved hypothetical ATPase. Homology to MCA0262 of Methylococcus capsulatus of 68% (gi|53756248|gb|AAU90539.1|(NBCI ENTREZ)). InterPro: AAA-protein (ATPases associated with various cellular activities) (IPR003959);AAA ATPase superfamily (IPR003593) Pfam: ATPase family associated with various cellular activities (domaine from 365 aa to 540 aa) no signal peptide. no TMHs; Function unclear.
     
  0.641
azo3737
Putative secreted protein; Conserved hypothetical protein. Homology to NE0192 of N.europaea of 52% (trembl:Q82XR2). Has PF04380, Protein of unknown function (DUF526);IPR007475; This is a family of uncharacterised proteins. No signal peptide. No TMHs.
       0.639
flgG
Flagellar basal-body rod protein flgG (Distal rod protein). The rod has been shown to consist of four different, yet evolutionary related proteins: in the distal portion of the rod there are about 26 subunits of protein flgG and in the proximal portion there are about six subunits each of proteins flgB, flgC, and flgF. These four proteins contain a highly conserved asparagine-rich domain at their N terminus. InterPro: Flagella basal body rod protein no signal peptide no TMHs; High confidence in function and specificity.
   
   0.510
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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