STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
glnKPII-like signal transmitter proteins are involved in the regulation of ammonium assimilation and nitrogen fixation. The PII-like proteins differed from each other in details of N-sensing. They were covalently modified by uridylylation upon nitrogen limitation. Similar to trembl|Q9EZQ3 (100%) and to trembl|Q7NQY3 (87%). Pfam: Nitrogen regulatory protein P-II; High confidence in function and specificity. (112 aa)    
Predicted Functional Partners:
amtB
Ammonium transporter 1 member 1 (AtAMT1;1). Involved in high affinity ammonium uptake. TREMBL:Q8RP89: 100% identity (published) InterPro:IPR001905; Ammonium_transpt. IPR002229; RhesusRHD. IPR010256; RH_like_transpt. Pfam: PF00909; Ammonium_transp PRINTS PR00342; RHESUSRHD. TIGRFAMs TIGR00836; amt; PROSITE: PS01219; AMMONIUM_TRANSP SignalP predicted signal peptide present (0.997 probability). TMHMM predicted 12 transmembrane helices; High confidence in function and specificity.
 0.997
amtD
Probable ammonia permease; Putative ammonium transporter MJ1343. A number of evolutionarily-related proteins have been found to be involved in the transport of ammonium ions across membranes.Represent a family of high affinity ammonium transporters. These proteins are highly hydrophobic and seem to contain from 10 to 12 transmembrane domain. TREMBL:Q88L29: 73% identity, 84% similarity InterPro: Ammonium transporter family InterPro: IPR001905; Ammonium_transpt. IPR010256; RH_like_transpt. Pfam: PF00909; Ammonium_transp; 1. PROSITE: PS01219; AMMONIUM_TRANSP amt: ammonium transporter Non [...]
 0.991
amtY
Ammonium transporter 1 member 2 (LeAMT1;2). Involved in high affinity ammonium uptake. TREMBL:Q8RP88: 100% identity (published) InterPro: IPR001905; Ammonium_transpt. IPR010256; RH_like_transpt. Pfam: PF00909; Ammonium_transp amt: ammonium transporter SignalP predicted signal peptide (probability 0.999) TMHMM predicted 11 transmembrane helices; High confidence in function and specificity.
 0.984
amtE
Probable ammonia permease with sensory box/GGDEF domains; Putative ammonium transporter with sensory/GGDEF boxes. TREMBL:Q88M14: 50% identity; 65% similarity; TREMBL:Q7UK31: 46% identity; 58% siilarity InterPro:IPR001633; EAL. IPR000160; GGDEF. IPR001610; PAC. IPR000014; PAS_domain. IPR001905; Ammonium_transpt. IPR003594; ATPbind_ATPase Pfam: PF00563; EAL; PF00990; GGDEF; PF00785; PAC; PF00989; PAS; PF00909; Ammonium_transp SMART SM00267; DUF1; SM00052; DUF2; SM00086; PAC; SM00091; PAS amt: ammonium transporter Nonsecretory protein with signal peptide (SignalP predicted). Presence of 1 [...]
 0.934
ntrB
Nitrogen regulation protein NR(II),; High confidence in function and specificity.
  
 0.899
glnD
Putative protein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
 
 
 0.882
argB
ArgB protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
 
 
 0.830
argA
Amino-acid N-acetyltransferases acting mainly on glutamate in the first step of the 'acetylated' ornithine biosynthesis pathway. For this reason it is also called N-acetylglutamate synthase. The enzyme may also act on aspartate. Similar to sprot|ARGA_YERPE (44%) and to sprot|ARGA_ECOLI (43%). Pfam (PF00696): Aspartokinase superfamily Pfam (PF00583): GCN5-related N-acetyltransferase; Specificity unclear.
   
 
 0.822
pilS
Two component system sensor protein,; High confidence in function and specificity.
  
 0.759
draG1
Probable ADP-ribosyl-[dinitrogen reductase] hydrolase. Homology to draG of R. rubrum of 44% (sprot|DRAG_RHORU) Involved in the regulation of the nitrogen fixation activity by the reversible ADP-ribosylation of the dinitrogenase reductase component of the nitrogenase enzyme complex. The ADP-ribosyltransferase (DraT) transfers the ADP-ribose group from NAD to dinitrogenase reductase. The ADP-ribose group is removed through the action of the ADP-ribosylglycohydrolase (DraG). Pfam: ADP-ribosylglycohydrolase no signal peptide no TMHs.
    
 
 0.665
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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