STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3757Modification methylase TaqI (EC 2.1.1.72) (Adenine-specific methyltransferase TaqI) (M.TaqI). THIS METHYLASE RECOGNIZES THE DOUBLE-STRANDED SEQUENCE TCGA CAUSES SPECIFIC METHYLATION ON A-4 ON BOTH STRANDS AND PROTECTS THE DNA FROM CLEAVAGE BY THE TAQI ENDONUCLEASE. InterPro: N6 adenine-specific DNA methyltransferase N12 class; Family membership. (418 aa)    
Predicted Functional Partners:
azo3662
Conserved hypothetical secreted proteinn. Homology to ebA3326 Azoarcus sp. EbN1 of 47% (gnl|keqq|eba:ebA3326(KEGG)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein.
 
     0.745
azo1368
Conserved hypothetical protein. Homology to ebA7035 of Azoarcus sp. EbN1 of 79% (gnl|keqq|eba:ebA7035(KEGG)). No domains predicted. No TMHs. No signal peptide.
  
     0.731
phaP
Putative phasin protein PhaP.A family of small proteins found associated with inclusions in bacterial cells. Most associate with polyhydroxyalkanoate (PHA) inclusions, the most common of which consist of polyhydroxybutyrate (PHB). These are designated granule-associate proteins or phasins. However, the member from Magnetospirillum sp. AMB-1 is called a magnetic particle membrane-specific GTPase. TrEMBL: Q93QF2 InterPro:IPR010127,TIGR01841 NO TMH Present No Signal Peptide Present; Family membership.
  
     0.714
azo2747
Conserved hypothetical protein. Homology to ebA6852 of Azoarcus sp. EbN1 of 47% (gnl|keqq|eba:ebA6852(KEGG)). No domains predicted. No TMHs. No signal peptide.
  
     0.706
npd2
NAD-dependent deacetylase 2 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 2). Modulates the activities of several enzymes which are inactive in their acetylated form. Similar to SWISSPROT: sprot|NPD2_PSEAE (50% Pseudomonas aeruginosa, Npd2) / sprot|NPD1_ARCFU (33% Archaeoglobus fulgidus, NpdA) InterPro: IPR003000 SIR2. Pfam: PF02146 Sir2 family; High confidence in function and specificity.
  
    0.690
fimV2
Putative type 4 pilus biogenesis; In Pseudomonas aeruginosa, FimV is probable involved in remodelling of the peptidoglycan layer to enable assembly of the type IV fimbrial structure and machinery. And it is also required for twitching motility. Similar to trembl|O87015 (26%). Pfam (PF05489): Phage Tail Protein X SignalP reporting Signal peptide; Function unclear.
  
     0.687
azo1698
Putative TetR family transcriptional regulator; Tetracycline repressor protein class G. Similar to SWISSPROT: sprot|TER7_VIBAN (21% Vibrio anguillarum (Listonella anguillarum), tetracycline repressor protein class G). TETR IS THE REPRESSOR OF THE TETRACYCLINE RESISTANCE ELEMENT; ITS AMINO-TERMINAL REGION FORMS A HELIX-TURN-HELIX STRUCTURE AND BINDS DNA. BINDING OF TETRACYCLINE TO TETR REDUCES THE REPRESSOR AFFINITY FOR THE TETRACYCLINE RESISTANCE GENE (TETA) PROMOTER OPERATOR SITES. InterPro: IPR001647 HTH_TetR. Pfam: PF00440 Bacterial regulatory proteins, tetR family. HTH reporting nu [...]
  
     0.684
azo1290
Conserved hypothetical protein. Homology to ebA98 of Azoarcus sp. EbN1 of 67% (gnl|keqq|eba:ebA983(KEGG)). No domains predicted. No signal peptide. No TMHs.
  
     0.674
azo3727
Conserved hypothetical secreted protein. Homology to ebA3180 of Azoarcus sp. EbN1 of 57% (gi|56477224|ref|YP_158813.1|(NBCI ENTREZ)). No domains predicted Signal Peptide present. No TMH reported present; Conserved hypothetical protein.
  
     0.663
azo1553
Conserved hypothetical protein, 39% identity to Swissprot;Q46825, ygfY of Escherichia coli. Has PF03937:(IPR005631, DUF339)TPR repeat region;This family represents a set of three divergent TPR repeats found in a small group of uncharacterised proteins. No Signal Peptide or TMH present; Family membership.
  
     0.656
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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