STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ntaBNitrilotriacetate monooxygenase component B (EC 1.14.13.-) (NTA monooxygenase component B) (NTA-MO B). HYDROXYLATION OF NITRILOTRIACETATE. TREMBL:Q7W4Q0: 46% identity, 65% similarity InterPro: Flavin reductase-like domain Interpro:IPR002563 Pfam:PF01613 No signal peptide No transmembrane helices monomer_idh: isocitrate dehydrogenase NA; High confidence in function and specificity. (164 aa)    
Predicted Functional Partners:
azo3524
Conserved hypothetical nitroreductase. Homology to cv1555 of C. violaceum of 72% (trembl|Q7NXS1). Involved in the reduction of nitrogen containing compounds. InterPro: Nitroreductase family (IPR000415). Pfam: Nitroreductase family. no signal peptide. no TMHs; Conserved hypothetical protein.
  
 
 0.837
ribF
Riboflavin kinase / FMN adenylyltransferase; Riboflavin biosynthesis protein ribF [Includes: Riboflavin kinase (EC 2.7.1.26) (Flavokinase); FMN adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase) (FAD synthetase)]. ribF: riboflavin biosynthesis protein R; High confidence in function and specificity; Belongs to the ribF family.
    
 0.815
xylE
Catechol 2,3-dioxygenase XylE catalyzes the ring cleavage of catechol and some substituted catechols. Similar to pir|JE0112 (52%), to trembl|Q45459 (48%)and to sprot|XYE2_PSEPU (50%). Pfam (PF00903): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ProDom (PD000977): Extradiol ring-cleavage dioxygenase; Specificity unclear.
  
 
 0.748
nfsA
Putative oxygen-insensitive NADPH nitroreductase. Homology to snrA of S. typhimurium of 37% (sprot|NFSA_SALTY) REDUCTION OF NITROAROMATIC COMPOUNDS USING NADH. REDUCES NITROFURAZONE BY A PING-PONG BI-BI MECHANISM POSSIBLY TO GENERATE A TWO-ELECTRON TRANSFER PRODUCT. MAJOR COMPONENT OF THE OXYGEN- INSENSITIVE NITROREDUCTASE ACTIVITY IN E.COLI. Pfam: Nitroreductase family no signal peptide no TMHs; Family membership; Belongs to the flavin oxidoreductase frp family.
  
 
 0.688
chrR
Probable chromate reductase. Homology to chrR of E. coli of 49% (tremblnew|AAK62985). Reduction of chromate (Cr(VI)) to Cr(III).no no signal peptide no TMHs; High confidence in function and specificity.
    
 0.663
ribE
Riboflavin synthase alpha chain (EC 2.5.1.9). Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1-D)- ribityl-amino-24(1H3H)-pyrimidinedione and L-34-dihydrohy-2- butanone-4-phosphate via 67-dimethyl-8-lumazine. The alpha subunit catalyzes the dismutation of 67-dimethyl-8-lumazine to riboflavin and 5-amino-6-(1-D)-ribityl-amino-24(1H3H)- pyrimidinedione. ribE: riboflavin synthase alpha subunit; High confidence in function and specificity.
    
 0.651
azo1998
Purine-nucleoside phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.
    
  0.611
gylR
Putative transcriptional regulator iclR-family,; Family membership.
 
  
 0.608
azo1962
Conserved hypothetical flavin reductase. Homology to rsc0763 of R. solanacearum of 43% (TREMBL:Q8Y1C7). Pfam: Flavin reductase like domain. This is a flavin reductase family consisting of enzymes known to be flavin reductases as well as various oxidoreductase and monooxygenase components. no signal peptide. no TMHs; Conserved hypothetical protein.
 
  
0.585
lapP
Phenol hydroxylase P5 protein (EC 1.14.13.7) (Phenol 2-monooxygenase P5 component). Probable electron transfer from NADPH via FAD and the 2Fe-2S center to the oxygenase activity site of the enzyme; High confidence in function and specificity.
  
 
 0.584
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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