STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3836Probable Iron-regulated outer membrane TonB-dependent receptor. 35% TonB_receptor.IPR010917; TonB_recept_C.IPR010105; TonB_siderophor. Pfam:PF00593; TonB_dep_Rec; 1. TIGRFAMs:TIGR01783; TonB-siderophor; 1. Signal peptide:present; Function unclear. (661 aa)    
Predicted Functional Partners:
pgtC
Putative regulatory lipoprotein; Phosphoglycerate transport regulatory protein pgtC precursor.Required for pgtP expression it may act jointly with the pgtA/pgtB signaling proteins.29% SBP_bac_1: Bacterial extracellular solute-binding protein family 1. Pfam:PF01547; SBP_bac_1; 1. Signal peptide:present; High confidence in function and specificity.
 
  
 0.868
azo3844
Putative TonB-dependent receptor; Region start changed from 4207859 to 4207739 (-120 bases).
  
 
 0.776
tonB2
Periplasmic biopolymer transport protein linking inner and outer membranes; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.693
tonB1
Putative TonB protein. Homology to tonb2 of P. aeruginosa of 39% (TREMBL:Q9RMT3). To complete transport of bound iron across the inner membrane, a second receptor complex is needed. The major component of this is tonB, a 27kDa protein that facilitates energy transfer from the proton motive force to outer receptors Pfam: Gram-negative bacterial TonB protein no signal peptide 1 TMH; Function unclear.
 
 
 0.692
azo2155
Conserved hypothetical secreted protein. Homology to rsc1270 of R. solanacearum of 44% (trembl|Q8XQF7(SRS)). no domains predicted .signal peptide present. no TMHs; Conserved hypothetical protein.
   
 
 0.691
azo3834
Conserved hypothetical protein. Homology to vv12967 of V. vulnificus of 47% (trembl|Q8D8K5). Pfam: DUF1111. no signal peptide. no TMHs.
 
     0.682
azo0699
Hypothetical secreted protein. No significant homology to the data bank. no domains pedicted. signal peptide. TMH in signal peptide.
    
 
 0.669
azo1264
Putative transmembrane sensor protein, no similarity to other bacterial proteins. Best hits to mus musculus and homo sapiens. Domains (LCCL_dom and TIR) are found in proteins (animal and plants) involved in protection against bacterial infection. InterPro: IPR004043 LCCL_dom. IPR000157 TIR. TMHMM reporting 1 transmembrane helices.
    
 
 0.669
azo2584
Conserved hypothetical protein; Similar to TREMBL:Q7NTT5 (32% identity).
    
 
 0.669
azo3123
Conserved hypothetical secreted protein. Homology to ebA651 of Azoarcus sp. EbN1 of 37% (gnl|keqq|eba:ebA651(KEGG)). InterproterPro (IPR000694): Proline-rich region. SignalP reporting signal peptide. no TMHs.
    
 
 0.669
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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