STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3844Putative TonB-dependent receptor; Region start changed from 4207859 to 4207739 (-120 bases). (758 aa)    
Predicted Functional Partners:
azo3836
Probable Iron-regulated outer membrane TonB-dependent receptor. 35% TonB_receptor.IPR010917; TonB_recept_C.IPR010105; TonB_siderophor. Pfam:PF00593; TonB_dep_Rec; 1. TIGRFAMs:TIGR01783; TonB-siderophor; 1. Signal peptide:present; Function unclear.
  
 
 0.776
azo3843
Putative exported protein.SignalP reporting signal peptice. Most likely cleavage site between pos. 27 and 28: AHA-AP; Function unclear.
       0.703
azo0235
Conserved hypothetical membrane protein. Homology to an orf of Rubrivivax gelatinosus of 55% (gi|47575633|ref|ZP_00245668.1|(NBCI ENTREZ)). No domains predicted. No signal peptide. 1 TMHs; Conserved hypothetical protein.
  
 
 0.617
tolA
Conserved hypothetical membrane protein. Homology to tolA of N. europaea of 39% (trembl|Q82XP0). no domains predicted InterPro: Proline-rich region (IPR000694) no signal peptide 1 TMHs; Conserved hypothetical protein.
  
 
 0.617
tonB1
Putative TonB protein. Homology to tonb2 of P. aeruginosa of 39% (TREMBL:Q9RMT3). To complete transport of bound iron across the inner membrane, a second receptor complex is needed. The major component of this is tonB, a 27kDa protein that facilitates energy transfer from the proton motive force to outer receptors Pfam: Gram-negative bacterial TonB protein no signal peptide 1 TMH; Function unclear.
  
 
 0.617
azo0708
Conserved hypothetical secreted protein. Homology to ne1626 of N. europaea of 46% (trembl|Q82U75) no domains predicted signal peptide TMH in signal peptide; Conserved hypothetical protein.
  
 
 0.617
tonB2
Periplasmic biopolymer transport protein linking inner and outer membranes; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 
 0.617
azo3746
Hypothetical secreted protein. No homology to the data bank. No domains predicted. signal peptide no TMHs.
  
 
 0.617
azo0649
Conserved hypothetical protein. Homology to ebA1795 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebA1795(KEGG)). No domains predicted. No TMHs.
    
 
 0.584
azo2042
Conserved hypothetical membrane protein. Homology to ebA436 of Azoarcus sp. EbN1 of 49% (gnl|keqq|eba:ebA436(KEGG)). No domains predicted. No signal peptide. TMHMM2 reporting presence of 2 TMH's; Conserved hypothetical protein.
    
 
 0.584
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.