STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
paaG6Putative enoyl-CoA hydratase paaG; Function:- Could possibly oxidizes fatty acids using specific components (By similarity). Activity:-(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O. Entry name:- SWISSPROT:PAAG_ECOLI InterPro:- IPR001753; EnCoA_hydrtse. Pfam:- PF00378; ECH; 1. Identities = 65/222 (29%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership. (285 aa)    
Predicted Functional Partners:
azo3685
Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices; Family membership.
    
 0.932
azo1817
Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...]
    
 0.931
hbdA
Probable 3-hydroxybutyryl-CoA dehydrogenase; Activity:- (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+ Entry name :- TREMBL:Q89GX2 Prim. accession # Q89GX2 Identities = 177/280 (63%) InterPro:- IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. IPR008927; 6DGDH_C_like. IPR000205; NAD_BS. Pfam :-PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. Prediction: Signal peptide Signal peptide probability: 0.873 Number of predicted TMHs: 0; Family membership.
 0.918
paaG4
Putative enoyl-CoA hydratase; COULD POSSIBLY OXIDIZES FATTY ACIDS USING SPECIFIC COMPONENTS (BY SIMILARITY). catalytic activity:-(3s)-3-hydroxyacyl-coa = trans-2(or 3)-enoyl- coa + H(2)o. Entry name:- SWISSPROT:PAAG_ECOLI InterPro:-IPR001753; EnCoA_hydrtse. Pfam:- PF00378; ECH; 1. Identities = 72/262 (27%) Number of predicted TMHs: 0; Family membership; Belongs to the enoyl-CoA hydratase/isomerase family.
 
  0.909
azo0694
Putative hybrid sensor and regulator protein,; Specificity unclear.
    
 0.906
azo2362
Putative sensor kinase/response regulator hybrid protein,; Specificity unclear.
    
 0.906
azo2450
Putative two-component system sensor protein,; Function unclear.
    
 0.906
abmC
Probable enoyl-CoA hydratase; Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O. Entry name TREMBL:Q93FB6 Identities = 224/280 (80%) Prim. accession # Q93FB6 InterPro IPR001753; EnCoA_hydrtse. Pfam PF00378; ECH; 1. Number of predicted TMHs: 0; High confidence in function and specificity; Belongs to the enoyl-CoA hydratase/isomerase family.
 
  0.897
fadA2
Probable 3-ketoacyl-CoA thiolase; Activity:- acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA Entry name:- SWISSPROT:THIK_ECOLI Prim. accession # P21151 InterPro:- IPR002155; Thiolase. Pfam:-PF02803; Thiolase_C; 1. PF00108; Thiolase_N; 1. Identities = 177/400 (44%) Number of predicted TMHs: 0; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.871
azo0655
Putative two-component sensor histidine kinase protein. TrEMBL; Q87XU6(47% identity, 64% similarity),Q6F9J5(43% identity,61% similarity),Q6NAD6(44% Identity,61% similarity). TMHMM2 reporting 2 TMH's present. No Signal peptide Present. Has PF02133;Permease for cytosine/purines, uracil, thiamine, allantoin: IPR001248;Cyt_pur_permease:The Nucleobase Cation Symporter-1 (NCS1) family consists of bacterial and yeast transporters for nucleobases including purines and pyrimidines. Members of this family possess twelve putative transmembrane a-helical spanners (TMSs). At least some of them have [...]
    
  0.859
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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