STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3872Conserved hypothetical secreted protein. Homology blr7490 of B.japonicum of 47% (trembl|Q89DE9(SRS)). No domains predicted .No TMHs. Signal peptide: present; Conserved hypothetical protein. (193 aa)    
Predicted Functional Partners:
azo3873
Putative glucase dehydrogenase alpha subunit. Homology to gdhalspha of B. cepacia of 31% (trembl|Q8GQE7). Pfam: GMC oxidoreductase no signal peptide no TMHs; Function unclear.
 
     0.894
gdhAlpha1
Putative glucose dehydrogenase alpha subunit. Homology to gdhAlpha of B. cepacia of 29% (trembl|Q8GQE7) InterPro: NAD binding site (IPR000205) Pfam: GMC oxidoreductase no signal peptide no TMHs; Function unclear.
 
     0.781
gdhAlpha2
Putative glucose dehydrogenase alpha subunit. Homology to gdhAlpha of B. cepacia of 28% (trembl|Q8GQE7). InterPro: NAD binding site (IPR000205); UBA/THIF-type NAD/FAD binding fold (IPR000594), $Fe-4s ferredoxin, ion-sulfur binding domain (IPR001450) Pfam: GMC oxidoreductase no signal peptide no TMHs gid: gid protein; Function unclear.
 
     0.759
azo3871
Putative lipoate protein ligase, has weak homology with hits. 35% identity with TrEMBL;Q81M24,Q818P0. Has Signal peptide. Has PF03099, Biotin/lipoate A/B protein ligase family;IPR004143 BPL_LipA_LipB; This family includes biotin protein ligase, lipoate-protein ligase A and B. Biotin is covalently attached at the active site of certain enzymes that transfer carbon dioxide from bicarbonate to organic acids to form cellular metabolites. Biotin protein ligase (BPL) is the enzyme responsible for attaching biotin to a specific lysine at the active site of biotin enzymes. Each organism probab [...]
 
     0.661
azo3869
Conserved hypothetical protein. Homology to oadh21d of H. volcanii of 33% (trembl|Q8U4T3). Pfam: Biotin-requiring enzyme. Interpro: Biotin/Lipoyl attachment (IPR000089). no signal peptide. no TMHs.
       0.605
azo3874
Conserved hypothetical secreted protein.
 
     0.582
azo3870
Hypothetical protein. Homology of the entire orf to the C-terminus of dihydrolipoamide acetyltransferase. Pfam: 2-0xo acid dehydrogenase acyltransferase no TMHs no signal peptide.
       0.580
dmpM
Phenol hydroxylase P2 protein (Phenol 2-monooxygenase P2 component)68% similarity to SWISSPROT:P19731,Pseudomonas sp DmpM or Phenol hydroxylase protein component P2, this protein lacks redox co-factors and is required for optimal turnover of Phenol hydroxylase. Phenol hydroxylase catabolises phenol and some of its methylated derivatives in the first step of phenol biodegradation, and is required for growth on phenol. The multicomponent enzyme is made up of P0, P1, P2, P3, P4 and P5 polypeptides. Pfam:PF02406, InterPro:IPR003454 91% similarity with hypothetical protein Rgel01002820 [Rub [...]
  
     0.457
acoA2
Probable acetoin dehydrogenase, alpha subunit. Homology to acoA of C. magnum of 42% (trembl|Q46142) CATALYZES THE 26-DICHLOROPHENOLINDOPHENOL-DEPENDENT CLEAVAGE OF ACETOIN INTO ACETATE AND ACETALDEHYDE IN VITRO. THE ALPHA SUBUNIT IS PROBABLY THE CATALYTIC SUBUNIT OF THE ENZYME. Pfam: Dehydrogenase E1 component no signal peptide no TMHs; Family membership.
 
     0.423
azo0751
Conserved hypothetical membrane protein. Homology to PA4820 of P. aeruginosa of 38% (trembl|Q9HUZ0(SRS)) Has PF04138, GtrA-like protein;IPR007267;Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylatio [...]
  
     0.419
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.