STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo3878Conserved hypothetical protein; Region start changed from 4252363 to 4252411 (-48 bases). (345 aa)    
Predicted Functional Partners:
azo3877
Conserved hypothetical protein. Homology to GSU3186 of G.sulfurreducens of 36% (tremblnew|AAR36577(SRS)). No domains predicted. No TMHs. No signal peptide.
 
  
 0.981
azo3876
Conserved hypothetical protein; Rhs family protein,vgrG 38% identity(54% similarity) to TrEMBL;Q747T8. TrEMBL;O52672. Signal Peptide Present. Has PF04524, Protein of unknown function,DUF586;IPR006533, Rhs_Vgr:This family contains a conserved region in several bacterial proteins of unknown function. These sequences represent the Vgr family of proteins,associated with some classes of Rhs elements. This model does not include a large octapeptide repeat region,VGXXXXXX, found in the Vgr of Rhs classes G and E. Has PF06715, Gp5 C-terminal repeat (2 copies);IPR010609,Gp5_C:This repeat compos [...]
 
     0.928
fabD
Probable malonyl CoA-acyl carrier protein transacylase. Homology to fabD of E. coli of 54% (sprot|FABD_ECOLI). Is involved in fatty acid biosynthesis and transfers the malonyl moeity from coenzyme A to acyl-carrier protein. InterPro: Acyl transferase domain (IPR001227); Manyl CoA-acyl carrier protein transaylase (IPR004410) Pfam: Acyl transferase domain Tigrfam: fabD: malonyl CoA-acyl carrier protein no signal peptide no TMHs; High confidence in function and specificity.
  
 
 0.927
azo3881
Conserved hypothetical protein. Homology to GSU3182 of G.sulfurreducens of 42% (tremblnew|AAR36573(SRS)). No domains predicted. No TMHs. No signal peptide.
 
    0.884
accD
Probable acetyl-coenzyme A carboxylase carboxyl transferase subunit b; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
 
 0.822
fabI1
Probable enoyl-acyl carrier protein reductase; CATALYTIC ACTIVITY: Acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH Entry name:- SWISSPROT:FABI_PSEAE Prim. accession # Q9ZFE4 Identities = 173/260 (66%) InterPro :- IPR002198; ADH_short. Pfam:- PF00106; adh_short; 1. Prediction: Non-secretory protein Signal peptide probability: 0.044 Number of predicted TMHs: 0; High confidence in function and specificity.
  
 
 0.784
fabI2
Probable enoyl-[acyl-carrier-protein] reductase; Catalytic activity :-acyl-[acyl-carrier protein] + nad(+) = trans- 2,3-dehydroacyl-[acyl-carrier protein] + nadh. pathway:- fatty acid biosynthesis pathway; second reduction step. Entry name SWISSPROT:FABI_ECOLI InterPro IPR002198; ADH_short. Identities = 108/252 (42%) Pfam PF00106; adh_short; 1. Prediction: Non-secretory protein Signal peptide probability: 0.00 Number of predicted TMHs: 0; High confidence in function and specificity.
  
 
 0.784
darB
3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41) (Beta- ketoacyl-ACP synthase III) (KAS III). Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids (By similarit [...]
  
 
 0.766
fabH
Probable 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
 
 0.766
azo0262
Hypothetical protein; Similar to TREMBL:Q9PFA7 (61% identity); TREMBL:Q87AD9 (61% identity); SWISSPROT:Q7VKH6 (34% identity); Function unclear; ORF1.
  
 0.760
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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