Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
azo3888Serine/threonine-protein kinase pknA (EC 2.7.11.1). Probably required for both normal cellular growth and differentiation. Inactivation of pknA leads to colonies that appear light green and rough in the absence of combined nitrogen. Pfam: Protein kinase domain; Family membership. (668 aa)    
Predicted Functional Partners:
azo0896
Putative phosphoprotein phosphatase,; Conserved hypothetical protein.
 
   0.829
azo1002
Putative phosphoprotein phosphatase,; Conserved hypothetical protein.
 
   0.829
azo3885
Putative phosphoprotein phosphatase,; Conserved hypothetical protein.
 
   0.829
pppL
Putative phosphoprotein phosphatase,; Family membership.
 
   0.826
azo3962
Putative phosphoprotein phosphatase,; Conserved hypothetical protein.
 
   0.826
azo1289
Putative serine/threonine protein kinase,; Family membership.
  
   0.786
azo3889
Conserved hypothetical protein. Homology to PA0076 of P.aeruginosa of 38% (trembl:Q9I756). No domains predicted. No TMHs. No signal peptide.
 
  
 0.755
azo3073
Hypothetical protein. No homology to the data base. Pfam: Protein tyrosine kinase, Protein kinase domain. Interpro: IPR000719 Protein kinase, IPR002290 Serine/threonine protein kinase, IPR001245 Tyrosine protein kinase, IPR011009 Protein kinase-like. No signal peptide. No TMHs.
  
     0.719
imcF
Conserved hypothetical ImcF-related protein. Homology to BPP0730 of Bordetella parapertussis of 45% (gnl|keqq|bpa:BPP0730(KEGG)). Has Signal Peptide. TMHMM2 reporting 2 TMH's present. Coils2 Program reporting presence of Coiled-Coil. Has PF06761, ImcF-related;IPR009612; This family represents a conserved region within several bacterial proteins that resemble ImcF, which has been proposed to be involved in Vibrio cholerae cell surface reorganisation, resulting in increased adherence to epithelial cells and increased conjugation frequency. Note that many family members are hypothetical p [...]
 
  
 0.701
azo1323
Probable protein kinase InterPro: Protein kinase,Protein kinase-like.
  
     0.661
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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