STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
imcFConserved hypothetical ImcF-related protein. Homology to BPP0730 of Bordetella parapertussis of 45% (gnl|keqq|bpa:BPP0730(KEGG)). Has Signal Peptide. TMHMM2 reporting 2 TMH's present. Coils2 Program reporting presence of Coiled-Coil. Has PF06761, ImcF-related;IPR009612; This family represents a conserved region within several bacterial proteins that resemble ImcF, which has been proposed to be involved in Vibrio cholerae cell surface reorganisation, resulting in increased adherence to epithelial cells and increased conjugation frequency. Note that many family members are hypothetical p [...] (1190 aa)    
Predicted Functional Partners:
ompA2
Putative outer membrane protein, OmpA family,36% identity(51%similarity) to TrEMBL;Q93IS0.TrEMBL;Q7AXY6(36% identity) TMHMM2 reporting presence of 1 TMH's. Has PF00691, OmpA family;IPR006665, OmpA/MotB:Most of the bacterial outer membrane proteins in this group are porin-like integral membrane proteins (such as ompA) MEDLINE:,but some are small lipid-anchored proteins.It is also found in MotB and related proteins. They are present in the outer membrane of many Gram-negative organisms; Conserved hypothetical protein.
 
 
 0.983
azo3889
Conserved hypothetical protein. Homology to PA0076 of P.aeruginosa of 38% (trembl:Q9I756). No domains predicted. No TMHs. No signal peptide.
 
  
 0.963
impJ
Conserved hypothetical protein,40% Identity (57% similarity)to TrEMBL;Q93EC4 Has PF05936, Bacterial protein of unknown function (DUF876);IPR010263;This family consists of a series of hypothetical bacterial sequences of unknown function.
 
 
 0.933
sciI
Putative cytoplasmic protein, sciI, 68% identity(80% similarity) to TrEMBL;Q93IS7. Has PF05943,Protein of unknown function (DUF877);IPR010269;This family consists of a number of uncharacterised bacterial proteins. The function of this family is unknown; High confidence in function and specificity.
 
 
 0.914
sciH
Putative cytoplasmic protein,sciH, 71% identity(87% similarity) to TrEMBL;Q7AXZ1. Has PF05591, Protein of unknown function (DUF770);IPR008312,UCP028301;This family consists of several proteins of unknown function from various bacterial species. These proteins are encoded in pathogenic and symbiotic bacteria as part of an operon (part of the SCI genomic island in Salmonella enterica and the imp locus in Rhizobium leguminosarum) implicated in pathogenicity and protein secretion.These proteins are SciH/ImpB; High confidence in function and specificity.
 
 
 0.896
azo1304
Hypothetical protein,63% identity (81% similarity) to TrEMBL;Q8XRT7. TrEMBL;Q7NR07(73% identity,86% similarity). Has (IPR010269)PF05943:Protein of unknown function (DUF877);This family consists of a number of uncharacterised bacterial proteins. The function of this family is unknown. No Signal peptide or TMH present; Function unclear.
 
 
 0.892
sciA
Putative cytoplasmic protein,sciA. TrEMBL;Q83SK5, Q7AXZ5 Has PF06812, ImpA-related N-terminal;IPR010657,ImpA_N;This family represents a conserved region located towards the N-terminal end of ImpA and related proteins. ImpA is an inner membrane protein, which has been suggested to be involved with proteins that are exported and associated with colony variations in Actinobacillus actinomycetemcomitans. Note that many family members are hypothetical proteins; Conserved hypothetical protein.
 
 
 0.892
azo3893
Conserved hypothetical secreted protein. Homology to PA1666 of P.aeruginosa of 37% (trembl|Q9I359(SRS)). Signal peptide present. No TMH or any other domains/features reported present; Conserved hypothetical protein.
 
  
 0.885
sciE
Putative cytoplasmic protein,sciE, 37% identity(52% similarity) to TrEMBL;Q93IT1. Has PF07024, ImpE protein;This family consists of several bacterial proteins including ImpE (Q93EC9) from Rhizobium leguminosarum. It has been suggested that the imp locus is involved in the secretion to the environment of proteins, including periplasmic RbsB protein, that cause blocking of infection specifically in pea plants.The exact function of this family is unknown; High confidence in function and specificity.
 
  
 0.867
sciB
Putative cytoplasmic protein, sciB. TrEMBl;Q93IT4(36% identity) Has PF06996;Protein of unknown function (DUF1305);IPR010732; This family consists of several hypothetical bacterial proteins of around 300 residues in length. The function of this family is unknown although one member (Q93IT4) from Salmonella enterica is thought to be involved in virulence; Conserved hypothetical protein.
 
 
 0.867
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.