Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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sciAPutative cytoplasmic protein,sciA. TrEMBL;Q83SK5, Q7AXZ5 Has PF06812, ImpA-related N-terminal;IPR010657,ImpA_N;This family represents a conserved region located towards the N-terminal end of ImpA and related proteins. ImpA is an inner membrane protein, which has been suggested to be involved with proteins that are exported and associated with colony variations in Actinobacillus actinomycetemcomitans. Note that many family members are hypothetical proteins; Conserved hypothetical protein. (353 aa)    
Predicted Functional Partners:
sciB
Putative cytoplasmic protein, sciB. TrEMBl;Q93IT4(36% identity) Has PF06996;Protein of unknown function (DUF1305);IPR010732; This family consists of several hypothetical bacterial proteins of around 300 residues in length. The function of this family is unknown although one member (Q93IT4) from Salmonella enterica is thought to be involved in virulence; Conserved hypothetical protein.
 
 
 0.977
azo1309
Conserved hypothetical protein. Homology to CV3967 of C.violaceum of 45% (tremble:Q7NR18) Has (IPR010732)PF06996:Protein of unknown function (DUF1305);This family consists of several hypothetical bacterial proteins of around 300 residues in length. The function of this family is unknown although one member (Q93IT4) from Salmonella enterica is thought to be involved in virulence. No signal peptide or TMH reported present.
 
 
 0.973
sciH
Putative cytoplasmic protein,sciH, 71% identity(87% similarity) to TrEMBL;Q7AXZ1. Has PF05591, Protein of unknown function (DUF770);IPR008312,UCP028301;This family consists of several proteins of unknown function from various bacterial species. These proteins are encoded in pathogenic and symbiotic bacteria as part of an operon (part of the SCI genomic island in Salmonella enterica and the imp locus in Rhizobium leguminosarum) implicated in pathogenicity and protein secretion.These proteins are SciH/ImpB; High confidence in function and specificity.
 
 
 0.947
sciI
Putative cytoplasmic protein, sciI, 68% identity(80% similarity) to TrEMBL;Q93IS7. Has PF05943,Protein of unknown function (DUF877);IPR010269;This family consists of a number of uncharacterised bacterial proteins. The function of this family is unknown; High confidence in function and specificity.
 
 
 0.939
impJ
Conserved hypothetical protein,40% Identity (57% similarity)to TrEMBL;Q93EC4 Has PF05936, Bacterial protein of unknown function (DUF876);IPR010263;This family consists of a series of hypothetical bacterial sequences of unknown function.
 
 
 0.918
azo3889
Conserved hypothetical protein. Homology to PA0076 of P.aeruginosa of 38% (trembl:Q9I756). No domains predicted. No TMHs. No signal peptide.
 
 
 0.917
azo3876
Conserved hypothetical protein; Rhs family protein,vgrG 38% identity(54% similarity) to TrEMBL;Q747T8. TrEMBL;O52672. Signal Peptide Present. Has PF04524, Protein of unknown function,DUF586;IPR006533, Rhs_Vgr:This family contains a conserved region in several bacterial proteins of unknown function. These sequences represent the Vgr family of proteins,associated with some classes of Rhs elements. This model does not include a large octapeptide repeat region,VGXXXXXX, found in the Vgr of Rhs classes G and E. Has PF06715, Gp5 C-terminal repeat (2 copies);IPR010609,Gp5_C:This repeat compos [...]
 
  
 0.905
ompA2
Putative outer membrane protein, OmpA family,36% identity(51%similarity) to TrEMBL;Q93IS0.TrEMBL;Q7AXY6(36% identity) TMHMM2 reporting presence of 1 TMH's. Has PF00691, OmpA family;IPR006665, OmpA/MotB:Most of the bacterial outer membrane proteins in this group are porin-like integral membrane proteins (such as ompA) MEDLINE:,but some are small lipid-anchored proteins.It is also found in MotB and related proteins. They are present in the outer membrane of many Gram-negative organisms; Conserved hypothetical protein.
 
  
 0.904
azo1307
Probable vgr-related protein,41% identity (55% similarity) to TrEMBL;Q7NY43. TrEMBL;Q8XSF8 Has (IPR006533 Rhs_Vgr)PF04524:Protein of unknown function, DUF586;This family contains a conserved region in several bacterial proteins of unknown function. Coils2 program predicts presence of a coiled coil.
 
  
 0.902
vgrG
Probable vgr-related protein, 44% identity(54% similarity) to TrEMBL; Q7P238.TrEMBL;Q8XRU3(44% identity). Signal Peptide Present. Has SMART;SM00438,Repressor of transcription;IPR000967, Znf_NFX1;This domain is presumed to be a zinc binding domain. The following pattern describes the zinc finger: C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-C,where X can be any amino acid, and numbers in brackets indicate the number of residues. The two position can be either his or cys. This domain is found in the human transcriptional repressor NK-X1, a repressor of HLA-DRA transcription; the Drosoph [...]
 
  
 0.902
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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