STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3920Conserved Hypothetical protein, Most Hits in the data base suggest to Pteridine-dependent deoxygenase like protein,TrEMBL;Q8P3Q5. Has PF01042 Endoribonuclease L-PSP,(IPR006175:Endoribon_LPSP);This domain is found in endoribonuclease, that is active on single-stranded mRNA and inhibits protein synthesis by cleavage of mRNA. Previously it was thought to inhibit protein synthesis initiation.This endoribonuclease may also be involved in the regulation of purine biosynthesis. No Signal peptide or TMH present!; Family membership. (336 aa)    
Predicted Functional Partners:
azo3921
Conserved hypothetical protein. Homology to xcc4013 of X. campestris of 46% (trembl|Q8P3Q6). InterPro: Monooxygenases FAD binding domain (IPR002938); NAD binding site (IPR000205) Pfam: FAD binding domain; Monooxygenase FAD binding domain. no signal peptide. no TMHs.
 
   
 0.940
azo3918
Putative phospholipid biosynthesis acyltransferase,30% Identity to TrEMBL;Q8FJ00.Q8X6N6 Has Signal Peptide. Has SMART;SM00563, PlsC, Phosphate acyltransferases;Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
 
 
   0.882
mipA
MltA-interacting protein precursor. MAY SERVE AS A SCAFFOLD PROTEIN REQUIRED FOR THE FORMATION OF A COMPLEX WITH MRCB/PONB AND MLTA THIS COMPLEX COULD PLAY A ROLE IN ENLARGEMENT AND SEPTATION OF THE MUREIN SACCULUS; High confidence in function and specificity.
 
     0.876
azo3917
Glycosyltransferase; Specificity unclear.
 
     0.861
azo3922
Conserved hypothetical secred protein. Homology to xac4267 of X. axonopodis of 41% (trembl|Q8PES3). no domains predicted .signal peptide. no TMHs; Conserved hypothetical protein.
 
     0.857
azo3913
Conserved hypothetical protein; Entry name:- TREMBL:Q8Y2B1 Prim. accession # Q8Y2B1 Identities = 64/116 (55%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0.
 
     0.791
azo0260
Conserved hypothetical protein; Entry name:- TREMBL:Q87EI7 InterPro:- IPR000873; AMP-bind. Pfam:- PF00501; AMP-binding; 2. Identity :- 45% Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0.
 
  
 0.786
azo0256
Conserved hypothetical membrane protein. Homology to rsc0429 of R. solanacearum of 52% (trembl|Q8Y2A7). Tigrfam: 2A0604s01: protein-export membrane protein signal peptide 10 TMHs; Function unclear.
 
     0.780
azo3912
Conserved hypothetical protein. Homology to RSc0426 of R.solanacearum of 51% (trembl:Q8Y2B0). No domains predicted. No signal peptide. No TMHs.
 
     0.774
azo0257
Conserved hypothetical secreted protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
 
     0.764
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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