STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lrp2Probable leucine-responsive regulatory protein. Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different opreons; Lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes. Similar to SWISSPROT: sprot|LRP_ECOLI (49% Escherichia coli, leucine-responsive regulatory protein Lrp) InterPro: IPR000485 HTH_AsnC_lrp. Pfam: PF01037 AsnC family. HTH reporting nucleic acid binding motif; High confidence in function and specificity. (182 aa)    
Predicted Functional Partners:
cobA2
Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM). TIGRFAM: dph5: diphthine synthase; High confidence in function and specificity; Belongs to the precorrin methyltransferase family.
    
 0.695
birA
biotin--[acetyl-CoA-carboxylase] ligase; BirA bifunctional protein [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)]. birA acts both as a biotin-operon repressor and as the enzyme that synthesizes the corepressor, acetyl-coa:carbon- dioxide ligase. this protein also activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins. InterPro: Biotin--acetyl-CoA-carboxylase ligase birA_ligase: biotin--acetyl-CoA-carboxyla; Specificity unclear.
  
 
 0.653
pabB
Para-aminobenzoate synthase component I (EC 4.1.3.-) (ADC synthase). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE. InterPro: Anthranilate synthase component I and chorismate binding enzyme pabB: para-aminobenzoate synthase component I; Specificity unclear.
     
 0.602
dadA2
D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids.
 
     0.602
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
   
 0.534
mipA
MltA-interacting protein precursor. MAY SERVE AS A SCAFFOLD PROTEIN REQUIRED FOR THE FORMATION OF A COMPLEX WITH MRCB/PONB AND MLTA THIS COMPLEX COULD PLAY A ROLE IN ENLARGEMENT AND SEPTATION OF THE MUREIN SACCULUS; High confidence in function and specificity.
  
    0.513
azo3920
Conserved Hypothetical protein, Most Hits in the data base suggest to Pteridine-dependent deoxygenase like protein,TrEMBL;Q8P3Q5. Has PF01042 Endoribonuclease L-PSP,(IPR006175:Endoribon_LPSP);This domain is found in endoribonuclease, that is active on single-stranded mRNA and inhibits protein synthesis by cleavage of mRNA. Previously it was thought to inhibit protein synthesis initiation.This endoribonuclease may also be involved in the regulation of purine biosynthesis. No Signal peptide or TMH present!; Family membership.
       0.507
azo3921
Conserved hypothetical protein. Homology to xcc4013 of X. campestris of 46% (trembl|Q8P3Q6). InterPro: Monooxygenases FAD binding domain (IPR002938); NAD binding site (IPR000205) Pfam: FAD binding domain; Monooxygenase FAD binding domain. no signal peptide. no TMHs.
       0.507
azo3922
Conserved hypothetical secred protein. Homology to xac4267 of X. axonopodis of 41% (trembl|Q8PES3). no domains predicted .signal peptide. no TMHs; Conserved hypothetical protein.
       0.507
gltB
Ferredoxin-dependent glutamate synthase,; Specificity unclear.
     
 0.495
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.