| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| alr | daaA | azo3925 | azo0181 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanine aminotransferase (EC 2.6.1.21) (D-aspartate aminotransferase) (D-amino acid aminotransferase) (D-amino acid transaminase) (DAAT). Acts on the D-isomers of alanine Leucine aspartate glutamate aminobutyrate norvaline and asparagine (By similarity). InterPro: Aminotransferases class-IV; High confidence in function and specificity. | 0.890 |
| alr | dadA2 | azo3925 | azo3924 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids. | 0.820 |
| alr | gltB | azo3925 | azo3642 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.896 |
| alr | lrp2 | azo3925 | azo3923 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Probable leucine-responsive regulatory protein. Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different opreons; Lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes. Similar to SWISSPROT: sprot|LRP_ECOLI (49% Escherichia coli, leucine-responsive regulatory protein Lrp) InterPro: IPR000485 HTH_AsnC_lrp. Pfam: PF01037 AsnC family. HTH reporting nucleic acid binding motif; High confidence in function and specificity. | 0.531 |
| daaA | alr | azo0181 | azo3925 | D-alanine aminotransferase (EC 2.6.1.21) (D-aspartate aminotransferase) (D-amino acid aminotransferase) (D-amino acid transaminase) (DAAT). Acts on the D-isomers of alanine Leucine aspartate glutamate aminobutyrate norvaline and asparagine (By similarity). InterPro: Aminotransferases class-IV; High confidence in function and specificity. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.890 |
| daaA | dadA2 | azo0181 | azo3924 | D-alanine aminotransferase (EC 2.6.1.21) (D-aspartate aminotransferase) (D-amino acid aminotransferase) (D-amino acid transaminase) (DAAT). Acts on the D-isomers of alanine Leucine aspartate glutamate aminobutyrate norvaline and asparagine (By similarity). InterPro: Aminotransferases class-IV; High confidence in function and specificity. | D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids. | 0.590 |
| daaA | gcvP | azo0181 | azo1285 | D-alanine aminotransferase (EC 2.6.1.21) (D-aspartate aminotransferase) (D-amino acid aminotransferase) (D-amino acid transaminase) (DAAT). Acts on the D-isomers of alanine Leucine aspartate glutamate aminobutyrate norvaline and asparagine (By similarity). InterPro: Aminotransferases class-IV; High confidence in function and specificity. | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.404 |
| daaA | gltB | azo0181 | azo3642 | D-alanine aminotransferase (EC 2.6.1.21) (D-aspartate aminotransferase) (D-amino acid aminotransferase) (D-amino acid transaminase) (DAAT). Acts on the D-isomers of alanine Leucine aspartate glutamate aminobutyrate norvaline and asparagine (By similarity). InterPro: Aminotransferases class-IV; High confidence in function and specificity. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.438 |
| daaA | metH | azo0181 | azo3726 | D-alanine aminotransferase (EC 2.6.1.21) (D-aspartate aminotransferase) (D-amino acid aminotransferase) (D-amino acid transaminase) (DAAT). Acts on the D-isomers of alanine Leucine aspartate glutamate aminobutyrate norvaline and asparagine (By similarity). InterPro: Aminotransferases class-IV; High confidence in function and specificity. | Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.497 |
| dadA2 | alr | azo3924 | azo3925 | D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.820 |
| dadA2 | daaA | azo3924 | azo0181 | D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids. | D-alanine aminotransferase (EC 2.6.1.21) (D-aspartate aminotransferase) (D-amino acid aminotransferase) (D-amino acid transaminase) (DAAT). Acts on the D-isomers of alanine Leucine aspartate glutamate aminobutyrate norvaline and asparagine (By similarity). InterPro: Aminotransferases class-IV; High confidence in function and specificity. | 0.590 |
| dadA2 | gcvP | azo3924 | azo1285 | D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids. | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.792 |
| dadA2 | gcvT | azo3924 | azo1287 | D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids. | Glycine cleavage T proteins are part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein Similar to sprot|GCST_NITEU (60%). Pfam: Glycine cleavage T-protein (aminomethyltransferase) TIGRfam (TIGR00528): Glycine cleavage T-protein (aminomethyl transferase); High confidence in function and specificity. | 0.728 |
| dadA2 | gltB | azo3924 | azo3642 | D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.879 |
| dadA2 | lpdA | azo3924 | azo1371 | D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids. | Dihydrolipoamide dehydrogenase. Homology to lpdA of N. meningitides of 70% (trembl|Q59099). THE BRANCHED-CHAIN ALPHA-KETO DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF ALPHA-KETO ACIDS TO ACYL-COA AND CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE (E1) LIPOAMIDE ACYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3) (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); Pyridine nucleotide-disulphide oxidoreductase, classI (IPR001100); biotin/Lipoyl attachment (IPR000089) [...] | 0.592 |
| dadA2 | lrp2 | azo3924 | azo3923 | D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids. | Probable leucine-responsive regulatory protein. Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different opreons; Lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes. Similar to SWISSPROT: sprot|LRP_ECOLI (49% Escherichia coli, leucine-responsive regulatory protein Lrp) InterPro: IPR000485 HTH_AsnC_lrp. Pfam: PF01037 AsnC family. HTH reporting nucleic acid binding motif; High confidence in function and specificity. | 0.601 |
| dadA2 | metH | azo3924 | azo3726 | D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids. | Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.618 |
| dadA2 | ooxA | azo3924 | azo0210 | D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids. | Putative opine oxidase subunit A. Homology to ooxA of A. tumefaciens of 37% (sprot|OOXA_AGRT4). OXIDATIVE CLEAVAGE OF OCTOPINE INTO L-ARGININE AND PYRUVATE (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327), NAD-bining site (IPR000205) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership. | 0.838 |
| dadA2 | soxF | azo3924 | azo1141 | D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids. | Probable sulfide dehydrogenase, falvoprotein subunit (Flavocytochrome C flavoprotein subunit). Homology to fccB of C. vinosum of 40% (sprot|DHSU_CHRVI). Pfam: Pyridine nucleotide-disulphide oxidoreductase signal peptide no TMHs; Family membership. | 0.787 |
| gcvP | daaA | azo1285 | azo0181 | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | D-alanine aminotransferase (EC 2.6.1.21) (D-aspartate aminotransferase) (D-amino acid aminotransferase) (D-amino acid transaminase) (DAAT). Acts on the D-isomers of alanine Leucine aspartate glutamate aminobutyrate norvaline and asparagine (By similarity). InterPro: Aminotransferases class-IV; High confidence in function and specificity. | 0.404 |
