| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo3926 | ccmA | azo3926 | azo3936 | Conserved hypothetical protein. Homology to Daro03003529 of Dechloromonas aromatica of 39% (gi|41722979|ref|ZP_00149945.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMH. | Probable heme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | 0.489 |
| azo3926 | ccmB | azo3926 | azo3935 | Conserved hypothetical protein. Homology to Daro03003529 of Dechloromonas aromatica of 39% (gi|41722979|ref|ZP_00149945.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMH. | Probable heme exporter protein B; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | 0.489 |
| azo3926 | ccmC | azo3926 | azo3933 | Conserved hypothetical protein. Homology to Daro03003529 of Dechloromonas aromatica of 39% (gi|41722979|ref|ZP_00149945.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMH. | Probable heme exporter protein C; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.689 |
| azo3926 | ccmD | azo3926 | azo3932 | Conserved hypothetical protein. Homology to Daro03003529 of Dechloromonas aromatica of 39% (gi|41722979|ref|ZP_00149945.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMH. | Conserved hypothetical heme exporter protein D; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. | 0.689 |
| azo3926 | ccmE | azo3926 | azo3931 | Conserved hypothetical protein. Homology to Daro03003529 of Dechloromonas aromatica of 39% (gi|41722979|ref|ZP_00149945.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMH. | Probable cytochrome C-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. | 0.689 |
| azo3926 | ccmF | azo3926 | azo3930 | Conserved hypothetical protein. Homology to Daro03003529 of Dechloromonas aromatica of 39% (gi|41722979|ref|ZP_00149945.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMH. | Cytochrome c-type biogenesis protein ccmF. Homology to ccmF of E. coli of 63% (sprot|CCMF_ECOLI). REQUIRED FOR THE BIOGENESIS OF C-TYPE CYTOCHROMES. POSSIBLE SUBUNIT OF A HEME LYASE. Tigrfam: nerF: cytochrome c-type biogenesis protein ccmF Pfam: Cytochrome C assembly protein probably signal peptide probably 15 THMs; High confidence in function and specificity. | 0.689 |
| azo3926 | ccmG | azo3926 | azo3929 | Conserved hypothetical protein. Homology to Daro03003529 of Dechloromonas aromatica of 39% (gi|41722979|ref|ZP_00149945.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMH. | Probable thiol disulfide interchange protein. Involved in disulfide bond formation. Catalyzes a late reductive step in the assembly of periplasmic c-type cytochromes probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity). InterPro: Periplasmic protein thiol:disulfide oxidoreductase DsbE (IPR004799) Interpro: Thioredoxin (IPR006662) Tigrfam: dsbE: periplasmic protein thiol:disulfide axidoreductase, DsbE superfamily signal peptide Probable 1 TMH; Family membership. | 0.737 |
| azo3926 | cycH | azo3926 | azo3927 | Conserved hypothetical protein. Homology to Daro03003529 of Dechloromonas aromatica of 39% (gi|41722979|ref|ZP_00149945.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMH. | Conserved hyppthetical cytochrome c-type biogenesis protein CycH. Homology to cycH of Azoarcus sp. EbN1 of 50% (gnl|keqq|eba:ebA3526(KEGG)). REQUIRED FOR THE BIOGENESIS OF C-TYPE CYTOCHROMES. POSSIBLE SUBUNIT OF A HEME LYASE (BY SIMILARITY). signal peptide. 1 TMHs; Conserved hypothetical protein. | 0.773 |
| azo3926 | cycL | azo3926 | azo3928 | Conserved hypothetical protein. Homology to Daro03003529 of Dechloromonas aromatica of 39% (gi|41722979|ref|ZP_00149945.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMH. | Probable cytochrome C-type biogenesis protein CycL; Possible subunit of a heme lyase. | 0.773 |
| ccmA | azo3926 | azo3936 | azo3926 | Probable heme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Conserved hypothetical protein. Homology to Daro03003529 of Dechloromonas aromatica of 39% (gi|41722979|ref|ZP_00149945.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMH. | 0.489 |
| ccmA | ccmB | azo3936 | azo3935 | Probable heme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Probable heme exporter protein B; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | 0.999 |
| ccmA | ccmC | azo3936 | azo3933 | Probable heme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Probable heme exporter protein C; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.999 |
| ccmA | ccmD | azo3936 | azo3932 | Probable heme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Conserved hypothetical heme exporter protein D; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. | 0.946 |
| ccmA | ccmE | azo3936 | azo3931 | Probable heme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Probable cytochrome C-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. | 0.955 |
| ccmA | ccmF | azo3936 | azo3930 | Probable heme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Cytochrome c-type biogenesis protein ccmF. Homology to ccmF of E. coli of 63% (sprot|CCMF_ECOLI). REQUIRED FOR THE BIOGENESIS OF C-TYPE CYTOCHROMES. POSSIBLE SUBUNIT OF A HEME LYASE. Tigrfam: nerF: cytochrome c-type biogenesis protein ccmF Pfam: Cytochrome C assembly protein probably signal peptide probably 15 THMs; High confidence in function and specificity. | 0.933 |
| ccmA | ccmG | azo3936 | azo3929 | Probable heme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Probable thiol disulfide interchange protein. Involved in disulfide bond formation. Catalyzes a late reductive step in the assembly of periplasmic c-type cytochromes probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity). InterPro: Periplasmic protein thiol:disulfide oxidoreductase DsbE (IPR004799) Interpro: Thioredoxin (IPR006662) Tigrfam: dsbE: periplasmic protein thiol:disulfide axidoreductase, DsbE superfamily signal peptide Probable 1 TMH; Family membership. | 0.904 |
| ccmA | cycH | azo3936 | azo3927 | Probable heme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Conserved hyppthetical cytochrome c-type biogenesis protein CycH. Homology to cycH of Azoarcus sp. EbN1 of 50% (gnl|keqq|eba:ebA3526(KEGG)). REQUIRED FOR THE BIOGENESIS OF C-TYPE CYTOCHROMES. POSSIBLE SUBUNIT OF A HEME LYASE (BY SIMILARITY). signal peptide. 1 TMHs; Conserved hypothetical protein. | 0.908 |
| ccmA | cycL | azo3936 | azo3928 | Probable heme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Probable cytochrome C-type biogenesis protein CycL; Possible subunit of a heme lyase. | 0.918 |
| ccmB | azo3926 | azo3935 | azo3926 | Probable heme exporter protein B; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Conserved hypothetical protein. Homology to Daro03003529 of Dechloromonas aromatica of 39% (gi|41722979|ref|ZP_00149945.1|(NBCI ENTREZ)). no domains predicted. no signal peptide. no TMH. | 0.489 |
| ccmB | ccmA | azo3935 | azo3936 | Probable heme exporter protein B; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Probable heme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | 0.999 |