STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo3967Putative protease IV. homology to sspA of E. coli of 38% (sprot|SPPA_ECOLI). Digestion of the cleaved signal peptides. This activity is necessary to maintain proper secretion of mature proteins across the membrane. InterPro: Signal peptide peptidase SppA 67K type (IPR004634); Signal peptide peptidase SppA 36K type (IPR004635); Pepditase family U7 (IPR002142) Pfam: Peptidase family U7 Tigrfam: SppA_67K: signal peptide peptidase SppA; sppA_dom: signal peptide peptidase SppA no signal peptide probable 1 TMH; High confidence in function and specificity. (613 aa)    
Predicted Functional Partners:
thiG
Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
     
 0.568
trmB
Conserved hypothetical tRNA (guanine-N7-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
       0.565
azo3966
Hypothetical protein predicted by Glimmer/Critica. No homology of the entire protein with the data bank. No domains predicted. No signal peptide. No TMHs.
       0.528
azo3190
Conserved hypothetical protein; In part; Function unclear.
     
 0.452
thiS
Thiamine biosynthesis protein ThiS; Putative sulfur transfer protein involved in thimanin biosynsthesis; High confidence in function and specificity.
       0.447
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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