STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ampGAmpG protein. Probably acts as a permease in the beta-lactamase induction system and in peptidoglycan recycling.Belong to the BT1 family of proteins. Presence of DUF domains and signail peptide. 11 tranmembrane helices.36% identity and 50% similarity to E.coli AmpG protein.(JW0423) 2A0125: AmpG-related permease; Family membership. (506 aa)    
Predicted Functional Partners:
azo3976
Probable uracil-DNA glycosylase. Has PF03167,Uracil DNA glycosylase superfamily;IPR005122 UDNA_glycsylseSF; Uracil-DNA glycosylase is a DNA repair enzyme that excises uracil residues from DNA by cleaving the N-glycosylic bond. Uracil in DNA can arise as a result of misincorportation of dUMP residues by DNA polymerase or deamination of cytosine. The sequence of uracil-DNA glycosylase is extremely well conserved.
       0.690
azo1783
Conserved hypothetical membrane protein. Homology to ebA6946 of Azoarcus sp. EbN1 of 64% (gnl|keqq|eba:ebA6946(KEGG)). Pfam: Pospholipase D, active site motife; DedA family. no signal peptide. 6 TMHs; Conserved hypothetical protein.
  
  
  0.592
hylD
Putative HylD family secretion protein. Homology to hylD of E. coli of 24% (sprot|HLY4_ECOLI) Involved in the transport of hemolysin A. InterPro: HlyD family secretion protein; Gram-negative bacteril RTX secretion protein D Pfam: HylD family secretion protein no signal peptide no TMHs; Family membership.
  
 0.564
azo0835
Membrane fusion protein; The secretion of a number of proteins/molecules require the help of members belonging to the ABC transporter family and a membrane fusion protein belonging to the HlyD family,; Family membership.
  
 0.564
metH
Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.529
oprM2
Putative outer membrane efflux protein. Homology to orpM in P. aeruginosa of 36%. Component of an efflux system that confers multidrug or multible antibiotic resistence. Interpro: Outer membran efflux protein Pfam: Outer membran efflux protein signal peptide no TMHs; Family membership.
  
 
  0.516
oprM1
Probable outer membrane efflux protein. Homology to oprM of P. aeruginosa of 57%. Component of an efflux system that confers multidrug or multible antibiotic resistence. Pfam: Outer membrane efflux protein signal peptide no TMHS; Family membership.
  
 
  0.508
oprM3
Probable outer membrane efflux protein. Homology to oprM of P. aeruginosa of 47%. Component of an efflux system that confers multidrug or multible antibiotic resistence. InterPro: Outer membrane efflux protein Pfam: Outer membrane efflux protein signal peptide no TMHs; Family membership.
  
 
  0.498
nodT
Putative outer membrane efflux protein. Homology to nodT from Rhizobium leguminosarum of 20% over 432 aa. The OEP family (Outer membrane efflux protein)allow export of a variety of substrates in Gram negative bacteria. Most members of NodT family are likely to export primarily small molecules rather than proteins. InterPro: Outer membrane efflux protein. Pfam: Outer membrane efflux protein Signal peptide no TMHs; Family membership.
  
 
  0.496
pheA
Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity.
   
 
 0.490
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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