STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
kynATryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (288 aa)    
Predicted Functional Partners:
SDS18359.1
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
 
 0.988
SDS84900.1
Putative cyclase.
  
 
 0.823
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.769
SDT05941.1
Septum formation protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
    
   0.596
SDS54438.1
Alpha/beta hydrolase fold; Manually curated.
  
 
 0.577
SDS95256.1
Acetyl esterase/lipase.
  
 
 0.577
SDT40923.1
Acetyl esterase/lipase.
  
 
 0.577
SDS65903.1
Kynurenine formamidase.
  
 
 0.509
SDT22551.1
Kynurenine formamidase.
  
 
 0.509
SDT43571.1
Putative cyclase.
  
 
 0.509
Your Current Organism:
Microlunatus soli
NCBI taxonomy Id: 630515
Other names: CCM 7685, DSM 21800, M. soli, Microlunatus soli Kampfer et al. 2010, Microlunatus sp. CC-012602, strain CC-012602, strain CC-12602
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