STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDT45635.1Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1261 aa)    
Predicted Functional Partners:
SDS10583.1
5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.998
SDS61213.1
Methylenetetrahydrofolate reductase (NADPH); Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.993
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.976
SDT01750.1
O-acetylhomoserine sulfhydrylase.
  
 
 0.975
fhs
Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
  
 
 0.970
SDS61345.1
Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family.
  
 
 0.969
SDT39692.1
Cobalamin-independent synthase, Catalytic domain.
  
 
 0.969
SDT36838.1
Homoserine dehydrogenase.
  
 
 0.968
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
  
 
 0.965
SDS25616.1
Cystathionine gamma-lyase.
  
 
 0.960
Your Current Organism:
Microlunatus soli
NCBI taxonomy Id: 630515
Other names: CCM 7685, DSM 21800, M. soli, Microlunatus soli Kampfer et al. 2010, Microlunatus sp. CC-012602, strain CC-012602, strain CC-12602
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