Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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A0A2P5API64-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (395 aa)    
Predicted Functional Partners:
COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
  
  
 0.975
A0A2P5F720
Geranylgeranyl reductase/cyanobacteria.
  
 
 0.953
A0A2P5FUF5
Geranylgeranyl reductase/cyanobacteria.
  
 
 0.953
A0A2P5FL98
Solanesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.944
A0A2P5EB62
FAD/NAD(P)-binding domain containing protein.
     
 0.923
A0A2P5CQR5
S-ribosylhomocysteinase (LuxS).
     
 0.900
COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
 
 0.897
COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).
 
 
 0.880
A0A2P5C2H3
Isopentenyl-diphosphate delta-isomerase, type.
  
 
 0.846
A0A2P5EIK8
2-carboxy-1,4-naphthoquinone phytyltransferase.
    
 0.834
Your Current Organism:
Trema orientale
NCBI taxonomy Id: 63057
Other names: Celtis orientalis, Sponia africana, T. orientale, Trema africana, Trema africanum, Trema orientalis
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