STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2P5B8S7DNA polymerase alpha/epsilon. (430 aa)    
Predicted Functional Partners:
A0A2P5BFG3
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.998
A0A2P5BHB9
Transcription initiation factor.
    
 0.993
A0A2P5CEB6
CDC45 family.
   
 0.993
A0A2P5DVT7
DNA helicase; Belongs to the MCM family.
   
 0.993
A0A2P5BPQ1
DNA helicase; Belongs to the MCM family.
   
 0.991
A0A2P5E6W3
DNA helicase; Belongs to the MCM family.
   
 0.990
A0A2P5EFP9
Guanine nucleotide-binding protein, beta subunit.
   
 
 0.989
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 0.982
A0A2P5EE58
DNA helicase; Belongs to the MCM family.
   
 0.975
A0A2P5FUX2
Mini-chromosome maintenance protein; Belongs to the MCM family.
   
 0.975
Your Current Organism:
Trema orientale
NCBI taxonomy Id: 63057
Other names: Celtis orientalis, Sponia africana, T. orientale, Trema africana, Trema africanum, Trema orientalis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.