node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFJ47827.1 | dsbA | EBL_c27560 | EBL_c39440 | Outer membrane protein. | Thiol-disulfide interchange protein DsbA precursor. | 0.635 |
AFJ47827.1 | ftsN | EBL_c27560 | EBL_c38600 | Outer membrane protein. | Essential cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | 0.734 |
AFJ47827.1 | holD | EBL_c27560 | EBL_c33780 | Outer membrane protein. | DNA polymerase III; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.772 |
AFJ47827.1 | lolA | EBL_c27560 | EBL_c25240 | Outer membrane protein. | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.624 |
AFJ47827.1 | rlpB | EBL_c27560 | EBL_c27230 | Outer membrane protein. | LPS-assembly lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.400 |
AFJ47827.1 | tolB | EBL_c27560 | EBL_c26560 | Outer membrane protein. | tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.689 |
AFJ47827.1 | yicH | EBL_c27560 | EBL_c39300 | Outer membrane protein. | AsmA family protein; F1 sector, epsilon-subunit. | 0.686 |
AFJ47827.1 | zapB | EBL_c27560 | EBL_c38650 | Outer membrane protein. | Hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.769 |
dsbA | AFJ47827.1 | EBL_c39440 | EBL_c27560 | Thiol-disulfide interchange protein DsbA precursor. | Outer membrane protein. | 0.635 |
dsbA | dsbB | EBL_c39440 | EBL_c17840 | Thiol-disulfide interchange protein DsbA precursor. | Disulfide bond formation protein DsbB family; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. | 0.873 |
dsbA | ftsN | EBL_c39440 | EBL_c38600 | Thiol-disulfide interchange protein DsbA precursor. | Essential cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | 0.705 |
dsbA | holD | EBL_c39440 | EBL_c33780 | Thiol-disulfide interchange protein DsbA precursor. | DNA polymerase III; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.667 |
dsbA | lolA | EBL_c39440 | EBL_c25240 | Thiol-disulfide interchange protein DsbA precursor. | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.692 |
dsbA | rdoA | EBL_c39440 | EBL_c39450 | Thiol-disulfide interchange protein DsbA precursor. | Phosphotransferase enzyme family protein; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. | 0.812 |
dsbA | rlpB | EBL_c39440 | EBL_c27230 | Thiol-disulfide interchange protein DsbA precursor. | LPS-assembly lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.681 |
dsbA | tolB | EBL_c39440 | EBL_c26560 | Thiol-disulfide interchange protein DsbA precursor. | tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.667 |
dsbA | yicH | EBL_c39440 | EBL_c39300 | Thiol-disulfide interchange protein DsbA precursor. | AsmA family protein; F1 sector, epsilon-subunit. | 0.747 |
dsbA | zapB | EBL_c39440 | EBL_c38650 | Thiol-disulfide interchange protein DsbA precursor. | Hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.737 |
dsbB | dsbA | EBL_c17840 | EBL_c39440 | Disulfide bond formation protein DsbB family; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. | Thiol-disulfide interchange protein DsbA precursor. | 0.873 |
dsbB | lolA | EBL_c17840 | EBL_c25240 | Disulfide bond formation protein DsbB family; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. | Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.406 |