| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ackA-3 | acs | CH53_391 | CH53_1439 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.925 |
| ackA-3 | maeB | CH53_391 | CH53_551 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Malic enzyme, NAD binding domain protein. | 0.737 |
| ackA-3 | poxB | CH53_391 | CH53_185 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family. | 0.921 |
| ackA-3 | pta | CH53_391 | CH53_2510 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Pta: phosphate acetyltransferase. | 0.987 |
| ackA-3 | pta-2 | CH53_391 | CH53_392 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.999 |
| ackA-3 | yccX | CH53_391 | CH53_104 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Acylphosphatase family protein. | 0.908 |
| acs | ackA-3 | CH53_1439 | CH53_391 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.925 |
| acs | maeB | CH53_1439 | CH53_551 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Malic enzyme, NAD binding domain protein. | 0.564 |
| acs | poxB | CH53_1439 | CH53_185 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family. | 0.921 |
| acs | pta | CH53_1439 | CH53_2510 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pta: phosphate acetyltransferase. | 0.921 |
| acs | pta-2 | CH53_1439 | CH53_392 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.944 |
| acs | yccX | CH53_1439 | CH53_104 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Acylphosphatase family protein. | 0.900 |
| fmdA | yccX | CH53_862 | CH53_104 | acetamidase/Formamidase family protein. | Acylphosphatase family protein. | 0.900 |
| hspQ | rlmI | CH53_106 | CH53_105 | Hemimethylated DNA binding domain protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family. | Ribosomal RNA large subunit methyltransferase I; Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA. | 0.603 |
| hspQ | yccX | CH53_106 | CH53_104 | Hemimethylated DNA binding domain protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family. | Acylphosphatase family protein. | 0.428 |
| maeB | ackA-3 | CH53_551 | CH53_391 | Malic enzyme, NAD binding domain protein. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.737 |
| maeB | acs | CH53_551 | CH53_1439 | Malic enzyme, NAD binding domain protein. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.564 |
| maeB | poxB | CH53_551 | CH53_185 | Malic enzyme, NAD binding domain protein. | Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family. | 0.938 |
| maeB | pta-2 | CH53_551 | CH53_392 | Malic enzyme, NAD binding domain protein. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.558 |
| maeB | yccX | CH53_551 | CH53_104 | Malic enzyme, NAD binding domain protein. | Acylphosphatase family protein. | 0.499 |