| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH53_1342 | alr | CH53_1342 | CH53_2158 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.516 |
| CH53_1342 | amiB | CH53_1342 | CH53_1341 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | N-acetylmuramoyl-L-alanine amidase family protein. | 0.749 |
| CH53_1342 | mfd | CH53_1342 | CH53_4415 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.584 |
| CH53_1342 | miaA | CH53_1342 | CH53_1339 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.810 |
| CH53_1342 | mutL | CH53_1342 | CH53_1340 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.637 |
| CH53_1342 | nnr | CH53_1342 | CH53_1343 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | 0.935 |
| CH53_1342 | queG | CH53_1342 | CH53_1344 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | Epoxyqueuosine reductase. | 0.637 |
| CH53_1342 | recG | CH53_1342 | CH53_1824 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.522 |
| CH53_1342 | tsaD | CH53_1342 | CH53_2328 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | tRNA threonylcarbamoyl adenosine modification protein TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.880 |
| CH53_1342 | yeaZ | CH53_1342 | CH53_3817 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ. | 0.964 |
| alr | CH53_1342 | CH53_2158 | CH53_1342 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | 0.516 |
| alr | amiB | CH53_2158 | CH53_1341 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | N-acetylmuramoyl-L-alanine amidase family protein. | 0.506 |
| amiB | CH53_1342 | CH53_1341 | CH53_1342 | N-acetylmuramoyl-L-alanine amidase family protein. | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | 0.749 |
| amiB | alr | CH53_1341 | CH53_2158 | N-acetylmuramoyl-L-alanine amidase family protein. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.506 |
| amiB | miaA | CH53_1341 | CH53_1339 | N-acetylmuramoyl-L-alanine amidase family protein. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.888 |
| amiB | mutL | CH53_1341 | CH53_1340 | N-acetylmuramoyl-L-alanine amidase family protein. | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.867 |
| amiB | nnr | CH53_1341 | CH53_1343 | N-acetylmuramoyl-L-alanine amidase family protein. | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | 0.795 |
| amiB | queG | CH53_1341 | CH53_1344 | N-acetylmuramoyl-L-alanine amidase family protein. | Epoxyqueuosine reductase. | 0.521 |
| mfd | CH53_1342 | CH53_4415 | CH53_1342 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | 0.584 |
| mfd | mutL | CH53_4415 | CH53_1340 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.608 |