| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH53_1342 | amiB | CH53_1342 | CH53_1341 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | N-acetylmuramoyl-L-alanine amidase family protein. | 0.757 |
| CH53_1342 | mfd | CH53_1342 | CH53_4415 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.584 |
| CH53_1342 | miaA | CH53_1342 | CH53_1339 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.812 |
| CH53_1342 | mutL | CH53_1342 | CH53_1340 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.670 |
| CH53_1342 | nnr | CH53_1342 | CH53_1343 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | 0.943 |
| CH53_1342 | queG | CH53_1342 | CH53_1344 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | Epoxyqueuosine reductase. | 0.662 |
| CH53_1342 | rimN | CH53_1342 | CH53_1450 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | Telomere recombination family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.666 |
| CH53_1342 | trmD | CH53_1342 | CH53_806 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | tRNA (guanine(37)-N(1))-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.692 |
| CH53_1342 | tsaD | CH53_1342 | CH53_2328 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | tRNA threonylcarbamoyl adenosine modification protein TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.890 |
| CH53_1342 | yeaZ | CH53_1342 | CH53_3817 | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ. | 0.965 |
| amiB | CH53_1342 | CH53_1341 | CH53_1342 | N-acetylmuramoyl-L-alanine amidase family protein. | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | 0.757 |
| amiB | miaA | CH53_1341 | CH53_1339 | N-acetylmuramoyl-L-alanine amidase family protein. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.919 |
| amiB | mutL | CH53_1341 | CH53_1340 | N-acetylmuramoyl-L-alanine amidase family protein. | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.895 |
| amiB | nnr | CH53_1341 | CH53_1343 | N-acetylmuramoyl-L-alanine amidase family protein. | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | 0.750 |
| amiB | queG | CH53_1341 | CH53_1344 | N-acetylmuramoyl-L-alanine amidase family protein. | Epoxyqueuosine reductase. | 0.582 |
| mfd | CH53_1342 | CH53_4415 | CH53_1342 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | 0.584 |
| mfd | mutL | CH53_4415 | CH53_1340 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA mismatch repair MutL family protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.667 |
| mfd | trmD | CH53_4415 | CH53_806 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | tRNA (guanine(37)-N(1))-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.424 |
| mfd | yeaZ | CH53_4415 | CH53_3817 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ. | 0.423 |
| miaA | CH53_1342 | CH53_1339 | CH53_1342 | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE. | 0.812 |