Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sugEQuaternary ammonium compound-resistance protein sugE. (104 aa)    
Predicted Functional Partners:
mdtJ
Small Multidrug Resistance family protein; Catalyzes the excretion of spermidine.
 
  
 0.816
emrE2
Small Multidrug Resistance family protein; Catalyzes the excretion of spermidine.
 
  
 0.784
hlyD
type_I_hlyD: type I secretion membrane fusion, HlyD family protein.
   
  
 0.628
umuD
Protein umuD; Belongs to the peptidase S24 family.
      
 0.618
mdtK_2
MATE efflux family protein; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
   
  
 0.564
mdfA
Multidrug transporter MdfA.
      
 0.543
CH53_1359
Hypothetical protein.
       0.539
ecnB
Entericidin EcnA/B family protein.
       0.539
blc
Lipocalin-like domain protein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.
  
  
 0.489
b4155
EF-P lysine aminoacylase GenX; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
   
  
 0.448
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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