STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
shuAOuter membrane heme receptor ShuA. (665 aa)    
Predicted Functional Partners:
hemS
Hemin transport protein hemS.
 
   
 0.926
hmuT
Hemin-binding periplasmic protein hmuT.
 
  
 0.891
hemU
fecCD transport family protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.846
hmuV
Hemin import ATP-binding protein HmuV; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
 
   
 0.824
hemS-2
Hemin transport protein hemS.
 
   
 0.745
CH53_1923
Hypothetical protein; tonB_Cterm: TonB family C-terminal domain protein.
 
 
 0.685
hmuT-2
Hemin-binding periplasmic protein hmuT.
 
  
 0.673
tonB
Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 
 0.659
hemP
Hemin uptake hemP family protein.
  
  
 0.602
CH53_3902
Autotrans_barl: outer membrane autotransporter barrel domain protein.
  
 
 0.536
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.