| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH53_152 | lpxK | CH53_152 | CH53_150 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.760 |
| CH53_152 | msbA | CH53_152 | CH53_151 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2. | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.734 |
| CH53_3047 | dnaK | CH53_3047 | CH53_1077 | ABC transporter family protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.464 |
| CH53_3047 | msbA | CH53_3047 | CH53_151 | ABC transporter family protein. | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.511 |
| apxIB_1 | apxIB_2 | CH53_3939 | CH53_3941 | type_I_sec_HlyB: type I secretion system ATPase family protein. | type_I_sec_HlyB: type I secretion system ATPase family protein. | 0.800 |
| apxIB_1 | msbA | CH53_3939 | CH53_151 | type_I_sec_HlyB: type I secretion system ATPase family protein. | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.477 |
| apxIB_2 | apxIB_1 | CH53_3941 | CH53_3939 | type_I_sec_HlyB: type I secretion system ATPase family protein. | type_I_sec_HlyB: type I secretion system ATPase family protein. | 0.800 |
| apxIB_2 | msbA | CH53_3941 | CH53_151 | type_I_sec_HlyB: type I secretion system ATPase family protein. | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.479 |
| dnaK | CH53_3047 | CH53_1077 | CH53_3047 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | ABC transporter family protein. | 0.464 |
| dnaK | msbA | CH53_1077 | CH53_151 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.610 |
| hscA | msbA | CH53_642 | CH53_151 | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.468 |
| kdsD | lpxC | CH53_2250 | CH53_1012 | kpsF: sugar isomerase, KpsF/GutQ family protein. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.871 |
| kdsD | lpxK | CH53_2250 | CH53_150 | kpsF: sugar isomerase, KpsF/GutQ family protein. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.880 |
| kdsD | msbA | CH53_2250 | CH53_151 | kpsF: sugar isomerase, KpsF/GutQ family protein. | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.428 |
| lagD | msbA | CH53_891 | CH53_151 | ABC transporter family protein. | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.441 |
| lpxC | kdsD | CH53_1012 | CH53_2250 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | kpsF: sugar isomerase, KpsF/GutQ family protein. | 0.871 |
| lpxC | lpxK | CH53_1012 | CH53_150 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.880 |
| lpxC | msbA | CH53_1012 | CH53_151 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.421 |
| lpxK | CH53_152 | CH53_150 | CH53_152 | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2. | 0.760 |
| lpxK | kdsD | CH53_150 | CH53_2250 | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | kpsF: sugar isomerase, KpsF/GutQ family protein. | 0.880 |