STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
mmsAMMSDH: methylmalonate-semialdehyde dehydrogenase. (501 aa)    
Predicted Functional Partners:
nifJ
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase.
   
 0.925
fadA
acetyl-CoA C-acyltransferase FadA; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
   
 0.922
fadI
acetyl-CoA C-acyltransferase FadI; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
   
 0.922
acs
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
   
 0.920
scpB
enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.919
pta-2
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.917
iolB
myo_inos_iolB: 5-deoxy-glucuronate isomerase.
 
  
 0.911
yhdH
Putative quinone oxidoreductase YhdH.
   
 0.911
pduL
Propanediol utilization PduL family protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.
    
 0.908
scpC
ygfH_subfam: succinate CoA transferase family protein.
  
 
 0.908
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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