Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mtlAPTS system mannitol-specific EIICBA component. (640 aa)    
Predicted Functional Partners:
mtlD
Mannitol-1-phosphate 5-dehydrogenase.
 
 
 0.999
fruB
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 family protein.
 
0.994
fruA
FRU: PTS system, Fru family, IIB component domain protein.
 
  
 0.993
ptsH
Phosphocarrier protein HPr.
 
 
 0.990
por
Mannitol dehydrogenase Rossmann domain protein.
 
  
 0.958
fpr_1
PTS_HPr_: phosphocarrier, HPr family protein.
 
 
0.954
uxaB
Mannitol dehydrogenase Rossmann domain protein.
  
  
 0.951
fryA
PEP-utilizing enzyme, mobile domain protein.
  
 
 0.948
dhaM
PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM; Belongs to the PEP-utilizing enzyme family.
 
 
 
 0.910
yfbT
HAD-SF-IA-v1: HAD hydrolase, IA, variant 1 family protein.
    
  0.904
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.