STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
trxBTRX_reduct: thioredoxin-disulfide reductase. (320 aa)    
Predicted Functional Partners:
trxA
Thioredoxin: thioredoxin; Belongs to the thioredoxin family.
 
 0.996
sufS
Cysteine desulfurase, SufS family protein; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
 
 
  0.921
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
     
 0.920
trxA-2
Thioredoxin: thioredoxin.
 
 0.916
metB_2
cys/Met metabolism PLP-dependent enzyme family protein.
   
 
 0.906
metB-2
O-succinylhomoserine (thiol)-lyase; Cystathionine gamma-lyase-like protein.
   
 
 0.906
ahpC
Hypothetical protein; C-terminal domain of 1-Cys peroxiredoxin family protein.
  
 
 0.859
ybbN
Putative thioredoxin protein.
  
 
 0.789
bcsC
Tetratricopeptide repeat family protein.
  
 
 0.759
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.719
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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