STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metRBacterial regulatory helix-turn-helix, lysR family protein; Belongs to the LysR transcriptional regulatory family. (317 aa)    
Predicted Functional Partners:
metA
Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
   
    0.810
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
 
  
 0.741
cysL_1
Bacterial regulatory helix-turn-helix, lysR family protein; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
  
     0.537
dmlR_2
Bacterial regulatory helix-turn-helix, lysR family protein; Belongs to the LysR transcriptional regulatory family.
  
     0.523
dmlR_14
Hypothetical protein; Belongs to the LysR transcriptional regulatory family.
  
     0.521
metF
Fadh2: methylenetetrahydrofolate reductase [NAD(P)H]; Belongs to the methylenetetrahydrofolate reductase family.
   
  
 0.520
dmlR_6
Bacterial regulatory helix-turn-helix, lysR family protein; Belongs to the LysR transcriptional regulatory family.
  
     0.503
benM_1
Bacterial regulatory helix-turn-helix, lysR family protein; Belongs to the LysR transcriptional regulatory family.
  
     0.498
dmlR_5
Bacterial regulatory helix-turn-helix, lysR family protein; Belongs to the LysR transcriptional regulatory family.
  
     0.465
rpmJ-2
rpmJ_bact: ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
  
    0.464
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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