| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acs | csdB | CH53_1439 | CH53_1043 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family protein. | 0.902 |
| acs | fadB | CH53_1439 | CH53_2071 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.985 |
| acs | fadJ | CH53_1439 | CH53_438 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Fatty oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.960 |
| acs | mmsA | CH53_1439 | CH53_1598 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | MMSDH: methylmalonate-semialdehyde dehydrogenase. | 0.940 |
| acs | pduP_1 | CH53_1439 | CH53_3356 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde dehydrogenase family protein. | 0.935 |
| acs | pflB | CH53_1439 | CH53_1390 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pyr_form_ly_1: formate acetyltransferase. | 0.902 |
| acs | pflB-2 | CH53_1439 | CH53_161 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pyr_form_ly_1: formate acetyltransferase. | 0.902 |
| acs | pta-2 | CH53_1439 | CH53_392 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.944 |
| acs | scpB | CH53_1439 | CH53_4254 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.950 |
| acs | yhdH | CH53_1439 | CH53_2198 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Putative quinone oxidoreductase YhdH. | 0.910 |
| csdB | acs | CH53_1043 | CH53_1439 | PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family protein. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.902 |
| csdB | fadB | CH53_1043 | CH53_2071 | PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family protein. | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.835 |
| csdB | fadJ | CH53_1043 | CH53_438 | PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family protein. | Fatty oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.835 |
| csdB | mmsA | CH53_1043 | CH53_1598 | PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family protein. | MMSDH: methylmalonate-semialdehyde dehydrogenase. | 0.907 |
| csdB | pduP_1 | CH53_1043 | CH53_3356 | PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family protein. | Aldehyde dehydrogenase family protein. | 0.925 |
| csdB | pflB | CH53_1043 | CH53_1390 | PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family protein. | Pyr_form_ly_1: formate acetyltransferase. | 0.920 |
| csdB | pflB-2 | CH53_1043 | CH53_161 | PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family protein. | Pyr_form_ly_1: formate acetyltransferase. | 0.920 |
| csdB | pta-2 | CH53_1043 | CH53_392 | PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family protein. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.943 |
| csdB | scpB | CH53_1043 | CH53_4254 | PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family protein. | enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.900 |
| csdB | yhdH | CH53_1043 | CH53_2198 | PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family protein. | Putative quinone oxidoreductase YhdH. | 0.900 |