| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH53_14 | ptsN | CH53_14 | CH53_2243 | RNaseEG: ribonuclease, Rne/Rng family domain protein. | nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN. | 0.477 |
| CH53_14 | yhbJ | CH53_14 | CH53_2242 | RNaseEG: ribonuclease, Rne/Rng family domain protein. | Hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. | 0.758 |
| fryA | glmM | CH53_332 | CH53_1285 | PEP-utilizing enzyme, mobile domain protein. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.499 |
| fryA | ptsN | CH53_332 | CH53_2243 | PEP-utilizing enzyme, mobile domain protein. | nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN. | 0.496 |
| fryA | ptsN1 | CH53_332 | CH53_394 | PEP-utilizing enzyme, mobile domain protein. | Phosphotransferase enzyme II, A component. | 0.471 |
| fryA | ptsO | CH53_332 | CH53_2241 | PEP-utilizing enzyme, mobile domain protein. | Phosphocarrier protein NPr. | 0.810 |
| fryA | raiA | CH53_332 | CH53_2244 | PEP-utilizing enzyme, mobile domain protein. | Ribosome-associated inhibitor A; yfiA: ribosomal subunit interface protein. | 0.738 |
| fryA | yhbJ | CH53_332 | CH53_2242 | PEP-utilizing enzyme, mobile domain protein. | Hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. | 0.811 |
| glmM | fryA | CH53_1285 | CH53_332 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | PEP-utilizing enzyme, mobile domain protein. | 0.499 |
| glmM | yhbJ | CH53_1285 | CH53_2242 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. | 0.604 |
| licR | ptsN1 | CH53_2227 | CH53_394 | PRD domain protein. | Phosphotransferase enzyme II, A component. | 0.587 |
| licR | yhbJ | CH53_2227 | CH53_2242 | PRD domain protein. | Hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. | 0.517 |
| ptsN | CH53_14 | CH53_2243 | CH53_14 | nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN. | RNaseEG: ribonuclease, Rne/Rng family domain protein. | 0.477 |
| ptsN | fryA | CH53_2243 | CH53_332 | nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN. | PEP-utilizing enzyme, mobile domain protein. | 0.496 |
| ptsN | ptsO | CH53_2243 | CH53_2241 | nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN. | Phosphocarrier protein NPr. | 0.990 |
| ptsN | raiA | CH53_2243 | CH53_2244 | nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN. | Ribosome-associated inhibitor A; yfiA: ribosomal subunit interface protein. | 0.865 |
| ptsN | yhbJ | CH53_2243 | CH53_2242 | nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN. | Hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. | 0.856 |
| ptsN1 | fryA | CH53_394 | CH53_332 | Phosphotransferase enzyme II, A component. | PEP-utilizing enzyme, mobile domain protein. | 0.471 |
| ptsN1 | licR | CH53_394 | CH53_2227 | Phosphotransferase enzyme II, A component. | PRD domain protein. | 0.587 |
| ptsN1 | yhbJ | CH53_394 | CH53_2242 | Phosphotransferase enzyme II, A component. | Hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. | 0.517 |