STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
fruAFRU: PTS system, Fru family, IIB component domain protein. (561 aa)    
Predicted Functional Partners:
pfkB
1-phosphofructokinase; pfkB: 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.999
fpr_1
PTS_HPr_: phosphocarrier, HPr family protein.
 
 
 0.999
pfkB-2
6-phosphofructokinase isozyme 2; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.998
fruB
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 family protein.
 
  
 0.998
mtlA
PTS system mannitol-specific EIICBA component.
 
  
 0.993
fryA
PEP-utilizing enzyme, mobile domain protein.
 
  
 0.993
ptsH
Phosphocarrier protein HPr.
 
 
 0.986
dhaM
PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM; Belongs to the PEP-utilizing enzyme family.
 
  
 0.977
fbaA
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.968
xylA
xylose_isom_A: xylose isomerase; Belongs to the xylose isomerase family.
     
 0.952
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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