STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
macA_4RND_mfp: efflux transporter, RND family, MFP subunit. (349 aa)    
Predicted Functional Partners:
oprM_1
Outer membrane efflux family protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
 
 
 0.970
CH53_2444
Fusaric acid resistance family protein.
 
  
 0.949
CH53_2442
Putative membrane protein.
 
     0.941
CH53_2441
Amidohydrolase family protein.
 
     0.692
macB_5
ABC transporter family protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.643
macB_4
ABC transporter family protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.643
macB_1
ABC transporter family protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
  
 
 0.643
oprM_2
rND efflux system, outer membrane lipoprotein, NodT family.
 
 
 0.599
cusC_1
outer_NodT: efflux transporter, outer membrane factor (OMF) lipo, NodT family protein.
 
 
 0.566
emrB
efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 family protein; Belongs to the major facilitator superfamily.
  
 
 0.526
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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